Flavobacterium meningosepticum infection in a neonatal ward

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
B BruunG E Andersen

Abstract

An outbreak of infections due to Flavobacterium meningosepticum type C in a neonatal intensive care unit is described. During a period of two weeks, two infants developed meningitis and a third was colonized in the respiratory tract and had transient bacteremia. The two meningitis patients were treated with clindamycin, rifampicin and cefotaxime systemically, plus rifampicin intraventricularly. Bacteriological eradication was achieved within 48 h, and both infants recovered from the meningitis without apparent neurological sequelae; however, one infant died two months later of unrelated causes. Environmental surveillance cultures failed to demonstrate a reservoir for the epidemic strain, but other Flavobacterium strains were recovered. Two clinically healthy infants were found to be colonized in the nasopharynx with strains that were extremely difficult to differentiate phenotypically from the epidemic strain. Extensive characterization of strains is necessary in order to differentiate between strains and subsequently to determine a certain source of infection.

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Citations

Aug 1, 1997·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·P R HsuehK T Luh
Aug 18, 2009·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S MarakiE Galanakis
May 1, 1995·Diagnostic Microbiology and Infectious Disease·M G Cormican, R N Jones
Jan 4, 2013·Journal of Clinical and Diagnostic Research : JCDR·Meena DiasZevita Furtado
Nov 3, 2011·International Journal of Pediatrics·Mehmet Ceyhan, Melda Celik
Aug 28, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Serdal GüngörRiza Durmaz
Dec 26, 2018·The Journal of Critical Care Medicine·Manuela ArbuneVictorita Stefanescu

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