Abstract
In order to screen better flavone prescriptions of anti-Newcastle disease virus (NDV), four flavone ingredients of epimedium flavones (EF), baikal skullcap root flavones (BSRF), wild dendranthema flower flavones (WDFF), and sanchi flavones (SF) screened in previous experiments and their prescriptions were added into chicken embryo fibroblast monolayer with three drug-adding modes respectively. The cellular A(570) values, the highest virus inhibitory rates and the score based on virus inhibitory rate were calculated to compare their antiviral activity. In immune protective test, the effects of three preparations (EF-BSRF, EF-SF-WDFF-BSRF and EF-WDFF-BSRF screened by the results in vitro experiment) on NDV infection were compared in chickens vaccinated with ND vaccine then challenged with NDV. Blood was regularly sampled for serum antibody titer determination. The pathogenic and dead statuses of chickens were clinically examined. The results indicated that the A(570) values of the nine prescriptions, especially the foresaid three prescriptions at almost all concentrations in three drug-adding modes were significantly higher than that of the virus control group. The foresaid three prescriptions presented at the top five of the hig...Continue Reading
References
Jun 1, 1991·Journal of Virological Methods·H TakeuchiS Shigeta
Aug 6, 1998·Carbohydrate Research·T MaruyamaR J Linhardt
Aug 26, 1999·Trends in Biotechnology·M Vidal, H Endoh
Jul 6, 2004·International Immunopharmacology·Xiangfeng KongXiangrui Li
Sep 2, 2004·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Jie Zhang, Lie-Ming Xu
Mar 3, 2005·Journal of Agricultural and Food Chemistry·Katheline HuaDominique P Bureau
May 11, 2005·Vaccine·Deyun WangJiaguo Liu
Mar 8, 2006·Vaccine·Hong-Xiang Sun
Dec 1, 2006·Poultry Science·X-F KongC-B Yang
Dec 30, 2006·Molecular Nutrition & Food Research·Mendel Friedman
Dec 7, 2007·International Journal of Biological Macromolecules·Xiaoyan HuangJunling Sun
Aug 12, 2008·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·P SchnitzlerJürgen Reichling
Apr 21, 2009·Virus Research·Sang-Moo KangRichard W Compans
May 13, 2010·Small·Adam W PerrimanStephen Mann
Jan 18, 2011·International Journal of Biological Macromolecules·Yunpeng FanYu Jiang
Mar 8, 2012·Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·Jingli Wang, Chaofan Zhou
Jul 6, 2014·Veterinary Research Communications·Abdelfattah H EladlMostafa R Khalil
Citations
Mar 31, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Xia MaYunpeng Fan
Mar 2, 2016·British Poultry Science·M WangX-Y Zhang
Dec 17, 2014·Carbohydrate Polymers·Yun ChenYuanliang Hu
Aug 15, 2015·BMC Veterinary Research·Wen XiongYuanliang Hu
Feb 11, 2014·Carbohydrate Polymers·Yun ChenYuanliang Hu
Apr 8, 2017·Pharmaceutical Biology·Yun ChenJiaguo Liu
Oct 30, 2016·International Journal of Biological Macromolecules·Ke MingJiaguo Liu
Dec 9, 2016·Pharmaceutical Biology·Yun ChenJiaguo Liu
Jun 1, 2018·Journal of Immunology Research·Yu LiJinjie Wu
May 14, 2019·BioMed Research International·Hongxu DuJiaguo Liu
Feb 24, 2016·The Journal of Veterinary Medical Science·Yan JiaLiwen Hu
Feb 3, 2021·Natural Product Research·Yanchun HuYan Jia