PMID: 8953432Nov 1, 1996Paper

Flavones with antibacterial activity against cariogenic bacteria

Journal of Ethnopharmacology
M SatoY Ohkawa

Abstract

Methanolic extracts obtained from 13 plants were studied for their antibacterial activity against cariogenic bacteria. Among them, the extract from Artocarpus heterophyllus showed the most intensive activity. Serial chromatographic purifications offered two active compounds which were identified as 6-(3-methyl-1-butenyl)-5,2',4'-trihydroxy-3-isoprenyl-7-methoxy flavone and 5,7,2',4'-tetrahydroxy-6-isoprenylflavone. Both isolates completely inhibited the growth of primary cariogenic bacteria at 3.13-12.5 micrograms/ml. They also exhibited the growth inhibitory effects on plaque-forming streptococci. These phytochemical isoprenylflavones would be potent compounds for the prevention of dental caries.

References

Jul 1, 1992·Diagnostic Microbiology and Infectious Disease·L J Eron, L O Gentry
Apr 1, 1983·Biochemical Pharmacology·B Havsteen

❮ Previous
Next ❯

Citations

Jun 15, 2010·Journal of Natural Medicines·Enos Tangke ArungFerry Sandra
Jan 1, 2010·Acta Crystallographica. Section E, Structure Reports Online·G B ThippeswamyJ Shashidhara Prasad
Oct 1, 2011·Journal of Biomedicine & Biotechnology·Najihah Mohd HashimRusea Go
Sep 2, 2006·Biological & Pharmaceutical Bulletin·Enos Tangke ArungRyuichiro Kondo
Dec 5, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Gianmaria F FerrazzanoGiuseppe Palumbo
Jul 6, 2014·Canadian Journal of Microbiology·Jun Won Kang, Sharon Lafferty Doty
Sep 13, 2011·Journal of Comparative Pathology·Y JinD Lin
Dec 3, 2005·International Journal of Antimicrobial Agents·T P Tim Cushnie, Andrew J Lamb
Apr 10, 2015·Pharmaceutical Biology·Abdi Wira Septama, Pharkphoom Panichayupakaranant
Jun 24, 2015·Journal of Ethnopharmacology·Darley Maria OliveiraDomingos Tabajara de Oliveira Martins
Mar 27, 2015·The Cochrane Database of Systematic Reviews·Philip RileyHelen V Worthington
Feb 15, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gianmaria F FerrazzanoAntonino Pollio
Sep 19, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Moa MegersaKabaye Kumela Goro
Oct 13, 2018·Pakistan Journal of Biological Sciences : PJBS·Tanti JuwitaJutti Levita
Jun 4, 2019·Frontiers in Microbiology·Leen OthmanRoula M Abdel-Massih
May 25, 2013·Food Science and Technology International = Ciencia Y Tecnología De Los Alimentos Internacional·Sahar AmanShahina Naz
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Patchima SithisarnPongtip Sithisarn
Oct 9, 1999·Clinical Microbiology Reviews·M M Cowan
Jul 2, 2003·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·M SatoC Tokuda
Apr 13, 2010·Journal of Ethnopharmacology·U B Jagtap, V A Bapat

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.