Flavor preferences conditioned by intragastric polycose infusions: a detailed analysis using an electronic esophagus preparation

Physiology & Behavior
G Elizalde, A Sclafani

Abstract

The present series of experiments examined the rat's conditioned preference for flavors associated with intragastric (IG) Polycose infusions. Adult female rats were fitted with two chronic intragastric catheters and were trained to drink flavored water (CS+; e.g., cherry-water) paired with IG infusions of 32% Polycose. On alternate days a different flavor (CS-; grape-water) was paired with IG water infusions. The flavored water and chow were available 23 hr/day. In subsequent two-choice tests the rats displayed strong preferences for the CS+ flavor (up to 98%). The CS+ preference persisted for several weeks during extinction tests when both the CS+ and CS- were paired with IG water or with no infusions. The rats also preferred the CS+ to plain water which contrasts with the mild aversion naive rats display to the flavored water. The acquired preference for the CS+ flavor was not as strong, however, as the rats' innate preferences for the taste of saccharin or Polycose. Also, unlike their response to saccharin and Polycose, the rats' acceptance (absolute intake) of the CS+ flavor was not elevated. CS+ intake was increased, though, when saccharin was added to the flavored water. The rats reversed their flavor preference when the ...Continue Reading

References

Jun 1, 1978·Physiology & Behavior·F S KralyG P Smith
Sep 1, 1976·Behavioral Biology·J A DeutschP Roll
Feb 1, 1976·Behavioral Biology·J A DeutschA Puerto
Jan 1, 1989·Physiology & Behavior·I RamirezM I Friedman
Jan 1, 1987·Neuroscience and Biobehavioral Reviews·A Sclafani
Jul 1, 1988·Developmental Psychobiology·M Vigorito, A Sclafani
Apr 1, 1987·Journal of Experimental Psychology. Animal Behavior Processes·E D CapaldiJ P Bradford
Jan 1, 1987·Neuroscience and Biobehavioral Reviews·A Sclafani, J W Nissenbaum
Jan 1, 1985·Annals of the New York Academy of Sciences·P Rozin, D Zellner
Mar 1, 1972·Journal of Comparative and Physiological Psychology·D A BoothG M McSherry
Apr 1, 1971·Physiology & Behavior·S H RevuskyD V Chalmers
May 15, 1969·Annals of the New York Academy of Sciences·J Le Magnen
Nov 1, 1969·Journal of Comparative and Physiological Psychology·G L Holman
Apr 1, 1968·Journal of Comparative and Physiological Psychology·K T Borer
Feb 1, 1984·Physiology & Behavior·A Sclafani, S Xenakis

❮ Previous
Next ❯

Citations

May 4, 2005·Current Neurology and Neuroscience Reports·Susan E Swithers, Terry L Davidson
Mar 1, 1993·Physiology & Behavior·M Naito-HoopesQ R Rogers
May 1, 1994·Physiology & Behavior·K Ackroff, A Sclafani
Feb 1, 1994·Physiology & Behavior·I Ramirez
Jan 1, 1996·Physiology & Behavior·C C Horn, J C Mitchell
Jul 1, 1994·Pharmacology, Biochemistry, and Behavior·G P MarkB G Hoebel
Jan 1, 1994·Neuroscience and Biobehavioral Reviews·F Bellisle, C Perez
Sep 1, 1991·Brain Research Bulletin·A Sclafani
Sep 5, 2003·Physiology & Behavior·Anthony Sclafani, John I Glendinning
Aug 1, 1996·Physiology & Behavior·I Ramirez
Mar 27, 2001·Pharmacology, Biochemistry, and Behavior·K Ackroff, A Sclafani
Oct 12, 2002·Pharmacology, Biochemistry, and Behavior·Karen Ackroff, Anthony Sclafani
Oct 12, 2002·Pharmacology, Biochemistry, and Behavior·Karen Ackroff, Anthony Sclafani
May 22, 2003·Pharmacology, Biochemistry, and Behavior·Karen Ackroff, Anthony Sclafani
Sep 1, 1996·Nutrition·N E RowlandB H Li
Jan 1, 1995·Nutrition Research Reviews·P J Rogers
Mar 1, 1991·The Proceedings of the Nutrition Society·P J Rogers, J E Blundell
Jul 1, 1995·The Proceedings of the Nutrition Society·A Sclafani
Mar 24, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Anthony Sclafani, Karen Ackroff
May 25, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Yada Treesukosol, Alan C Spector
Feb 3, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Bart C De JongheMihai Covasa
Jul 27, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Anthony SclafaniRobert F Margolskee
Oct 7, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Steven ZukermanAnthony Sclafani
Jan 23, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Yada TreesukosolAlan C Spector

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.