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Flavoxate and 3-methylflavone-8-carboxylic acid. Assay methods in blood and urine, plasma-red cells repartition and stability

Arzneimittel-Forschung

Nov 1, 1975

Agata Cova, Ivo Setnikar

PMID: 1048

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Abstract

The following assay methods for pharmacokinetic studies on flavoxate (F) and on its main metabolite, i.e. 3-methylflavone-8-carboxylic acid (A), are described. 1. Spectrophotometry for the assay of F and of A in plasma, 2. TLC-Spectrodensitometry and GLC for the assay of A in urine afte...read more

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Canis familiaris
Drug Stability
Hydrolysis
Metazoa
Chinchilla Rabbits
Study, Methodological
Hydrogen-Ion Concentration
Spectrophotometry, Ultraviolet
In Vitro [Publication Type]
Chromatography, Gas-Liquid
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  • Flavoxate and 3-methylflavone-8-carboxylic acid. Assay methods in blood and urine, plasma-red cells repartition and stability

    Arzneimittel-Forschung

    Nov 1, 1975

    Agata Cova, Ivo Setnikar

    PMID: 1048

    DOI:

    Abstract

    The following assay methods for pharmacokinetic studies on flavoxate (F) and on its main metabolite, i.e. 3-methylflavone-8-carboxylic acid (A), are described. 1. Spectrophotometry for the assay of F and of A in plasma, 2. TLC-Spectrodensitometry and GLC for the assay of A in urine afte...read more

    Mentioned in this Paper

    Canis familiaris
    Drug Stability
    Hydrolysis
    Metazoa
    Chinchilla Rabbits

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