Flecainide intoxication

Journal of Analytical Toxicology
B LevineY H Caplan

Abstract

A fatal case attributed to flecainide intoxication is presented. Quantitation was by capillary gas chromatography with nitrogen-phosphorus detection. The flecainide concentration in the blood was 13 mg/L as compared to a therapeutic range in serum of 0.2-1.0 mg/L. Flecainide concentrations in other specimens were as follows: bile, 160 mg/L; urine, 54 mg/L; vitreous humor, 7.4 mg/L; liver, 180 mg/kg; kidney, 74 mg/kg; and stomach contents, 120 mg.

Citations

Feb 9, 2000·Forensic Science International : Synergy·N RomainP Mangin
Aug 26, 2003·Legal Medicine·M J Lynch, J Gerostamoulos
Jan 17, 2016·Forensic Science International : Synergy·F BévalotL Fanton
Dec 20, 2011·Legal Medicine·Cristian PalmiereFrank Sporkert
Jan 23, 2016·Forensic Toxicology·Fabien BévalotJérôme Guitton
Jun 3, 2004·Forensic Science International : Synergy·F MusshoffB Madea
Jul 7, 2017·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Robin E Ferner, Jeffrey K Aronson

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