Flow-induced choking of a compliant Hele-Shaw cell

Proceedings of the National Academy of Sciences of the United States of America
Finn BoxAnne Juel

Abstract

After centuries of striving for structural rigidity, engineers and scientists alike are increasingly looking to harness the deformation, buckling, and failure of soft materials for functionality. In fluidic devices, soft deformable components that respond to the flow have the advantage of being passive; they do not require external actuation. Harnessing flow-induced deformation for passive functionality provides a means of developing flow analogs of electronic circuit components such as fluidic diodes and capacitors. The electronic component that has so far been overlooked in the microfluidics literature-the fuse-is a passive safety device that relies on a controlled failure mechanism (melting) to protect a circuit from overcurrent. Here, we describe how a compliant Hele-Shaw cell behaves in a manner analogous to the electrical fuse; above a critical flux, the flow-induced deformation of the cell blocks the outflow, interrupting (choking) the flow. In particular, the pressure distribution within the fluid applies a spatially variant normal force to the soft boundary, which causes nonuniform deformation. As a consequence of lateral confinement and incompressibility of the soft material, this flow-induced elastic deformation mani...Continue Reading

References

Feb 15, 1992·Physical Review. a·H ZhaoJ V Maher
Jul 13, 2004·Physical Review Letters·J M Skotheim, L Mahadevan
May 21, 2005·Physical Review Letters·J AshmoreT Mullin
Aug 11, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Yonggang Y HuangAndrew G Alleyne
Oct 2, 2007·Nature Materials·Nak Won ChoiAbraham D Stroock
Mar 25, 2011·Lab on a Chip·Suresh NeethirajanFrancis Lin
Sep 8, 2012·Nature·Jeong-Yun SunZhigang Suo
Aug 6, 2013·Physical Review Letters·Talal T Al-HousseinyHoward A Stone
Oct 29, 2013·Physical Review Letters·John R ListerJerome A Neufeld
Apr 12, 2014·Science·Etienne DucrotCostantino Creton
Nov 10, 2015·Physical Review Letters·Zhong ZhengHoward A Stone
Dec 27, 2015·Physical Review Letters·Yumo WangJoelle Frechette
Oct 21, 2017·Physical Review Letters·Michael GomezDominic Vella
Nov 24, 2018·Nature Communications·Marcia A M M FerrazBart M Gadella
Jan 17, 2019·Nature Reviews. Cancer·Alexandra Sontheimer-PhelpsDonald E Ingber
Nov 9, 2019·Microsystems & Nanoengineering·Daniel MigliozziMartin A M Gijs

❮ Previous
Next ❯

Software Mentioned

MATLAB

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme
M MasudaK Fujiwara
© 2021 Meta ULC. All rights reserved