Flow-injection spectrophotometric determination of piroxicam

Journal of Pharmaceutical and Biomedical Analysis
C Sanchez-PedreñoJuan C Rodríguez

Abstract

Two flow-injection analysis (FIA) methods are proposed for the determination of piroxicam. The first involves measurement of the UV absorbance of a solution containing the drug, methanol and hydrochloric acid at 332 nm; in the second method a Fe(III)-piroxicam complex is formed in a methanolic medium and the absorbance is measured at 520 nm. In both methods, the peak height is used as a quantitative parameter and piroxicam is determined over the ranges 0.5-15 and 30-500 microgram ml-1, respectively. The methods have been applied to the routine determination of the drug in dosage forms.

Citations

Jun 16, 2005·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Mihály KádárPéter Huszthy
Feb 19, 2002·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·María Isabel Pascual-RegueraMaría Soledad Castro Ruiz
Jan 10, 2003·Chemical & Pharmaceutical Bulletin·Mohamed A El-RiesManal El-Shall
Mar 4, 2006·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Hamid AbdollahiAbdolhossein Naseri
Dec 13, 2006·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Idrees F Al-Momani

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