Flow Mediated Skin Fluorescence technique reveals remarkable effect of age on microcirculation and metabolic regulation in type 1 diabetes

Microvascular Research
Joanna KatarzynskaJerzy Gebicki

Abstract

Flow Mediated Skin Fluorescence (FMSF) is a novel technique for non-invasive evaluation of the microcirculation and metabolic regulation. This study describes the diagnostic potential of FMSF for type 1 diabetes (DM1). All study participants, in both the control (n = 31) and DM1 (n = 40) groups, were between the ages of 30-49 y. The patients in the DM1 group had all been suffering from diabetes for at least 10 y. The parameters HRindex, HRmax and MR inversely correlate with age and BMI. An unidentified compensatory effect was observed among the younger members of the DM1 group. The majority of DM1 patients with HRindex < 8% showed signs of dysfunctional metabolic regulation. FMSF appears to be an extremely useful technique for monitoring diabetic patients over time, enabling early diagnosis of potentially dysfunctional microcirculation and metabolic regulation.

Citations

Dec 20, 2019·Journal of Diabetes Science and Technology·Joanna KatarzynskaJerzy Gebicki
Jan 14, 2020·BioMed Research International·Jaroslaw BogaczewiczAnna Wozniacka
Apr 29, 2021·Vascular Health and Risk Management·Agnieszka Los-StegientaJerzy Gebicki
Apr 21, 2021·Expert Review of Respiratory Medicine·Marieta P TheodorakopoulouAfroditi K Boutou

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