PMID: 2122137Jan 1, 1990Paper

Flow-volume curves in obstructive sleep apnea and snoring

Lung
H RauscherH Zwick

Abstract

The diagnostic value of flow-volume curves for sleep apnea was studied in 32 patients with obstructive sleep apnea, 40 simple snorers, and 30 healthy nonsnorers. A sawtooth appearance of the flow-volume curve was seen in 22 of the sleep apnea patients (69%), 14 of the simple snorers (35%), and 10 of the nonsnorers (33%). The ratio of midexpiratory flow (FEF 50) to midinspiratory flow (FIF 50) was greater than 1 in 6 of the sleep apnea patients (19%), 3 of the simple snorers (8%), and 2 of the nonsnorers (7%). Thus, only the sawtooth sign was more frequently found in sleep apnea patients than in controls (p less than 0.01). Sleep apnea patients with a sawtooth appearance of the flow-volume curve had a higher apnea index (38.7 +/- 22 vs. 21.5 +/- 12.1; p less than 0.01) and lower nocturnal minimum oxygen saturation (68.1% +/- 16.8 vs. 81.3% +/- 9.97; p less than 0.01) than those without. In symptomatic snorers, sensitivity of the sawtooth sign for sleep apnea was 72% and specificity 61%, for a FEF50/FIF50 ratio above 1 sensitivity was 17% and specificity 83%. In asymptomatic patients, sensitivity of either sign was extremely poor (33%) and specificity was 67% for the sawtooth sign and 85% for FEF50/FIF50 greater than 1. We conclu...Continue Reading

References

Apr 1, 1979·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·R T Brouillette, B T Thach
Apr 1, 1989·The American Review of Respiratory Disease·V HoffsteinN Zamel
Nov 20, 1986·The New England Journal of Medicine·T D BradleyV Hoffstein
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Jun 26, 2001·Psychiatry and Clinical Neurosciences·T HoriUNKNOWN Sleep Computing Committee of the Japanese Society of Sleep Research Society

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Citations

Jul 28, 2010·Sleep & Breathing = Schlaf & Atmung·Ender Levent, Nesrin Sarıman
Jan 16, 2007·American Journal of Respiratory and Critical Care Medicine·Biao ZengPeter A Cistulli
Apr 7, 2009·Medicine and Science in Sports and Exercise·Matteo BoniniSergio Bonini
Dec 3, 2016·Sleep & Breathing = Schlaf & Atmung·Michael H BourneEric J Olson
May 29, 1999·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·V M AmadoP Tavares

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