PMID: 6404858Jan 1, 1983Paper

Fluctuations in the enzymatic activity of the human endometrium

Histochemistry
E A EliasA E Meijer

Abstract

Cyclic fluctuations were studied in the activity of oxidoreductases playing a role in the major energy metabolic pathways, lysosomal and non-lysosomal hydrolases and some non-enzymatic cytochemical components demonstrable in different developmental physiological or pathophysiological phases of human endometrium. The total scope of the study involved 170 tissues and cytological specimens. The cytological material included microcurettings, aspirates, brush preparations and tissue prints. An evaluation of the usefulness of the application of enzyme cytochemistry to cytological material is included. The most important results were a cyclic fluctuation and a progestagenic controlled increase in the activity of many oxidoreductases, especially the NADPH regenerating enzymes of the pentose phosphate pathway, and of the NADP+ dependent isocitrate dehydrogenase. The histochemical evaluation of the activity of these NADP+ linked enzymes can therefore be recommended for the evaluation of the physiological status of the endometrial cells, especially in patients with infertility problems.

References

Nov 1, 1975·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J Koudstaal
Dec 1, 1965·American Journal of Obstetrics and Gynecology·J M Craig, S Danziger
Oct 1, 1972·The Biochemical Journal·P C Wong, J F Henderson
Jun 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·H A LardyP Walter
Oct 1, 1965·The Journal of Obstetrics and Gynaecology of the British Commonwealth·L Bitensky, S Cohen
Jul 1, 1980·The Journal of Pathology·E A EliasD J Tazelaar
Jul 1, 1960·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·L W WATTENBERG, J L LEONG

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Citations

Oct 17, 1998·The Journal of Legal Medicine·M B Kapp
Mar 30, 2001·Memory & Cognition·C A MeissnerC M Kelley
May 19, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Kirstie L HaywoodSarah Chapman

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