Fluid administration and morbidity in transhiatal esophagectomy

The Journal of Surgical Research
Oliver S EngDarren R Carpizo

Abstract

Esophagectomy is associated with significant morbidity. Optimizing perioperative fluid administration is one potential strategy to mitigate morbidity. We sought to investigate the relationship of intraoperative fluid (IOF) administration to outcomes in patients undergoing transhiatal esophagectomy with particular attention to malnourished patients, who may be more susceptible to the effects of fluid overload. Patients who underwent transhiatal esophagectomy from 2000-2013 were identified from a retrospective database. IOF rates (mL/kg/hr) were determined and their relationship to outcomes compared. To examine the impact of malnutrition, we stratified patients based on median preoperative serum albumin and compared outcomes. 211 patients comprised the cohort. 74% of patients underwent esophagectomy for esophageal adenocarcinoma. Linear regression analyses were performed comparing independent perioperative variables to four outcomes variables: length of stay, complications per patient, major complications, and Clavien-Dindo classification. IOF rate was significantly associated with three of four outcomes on univariate analysis. Significantly more patients with a preoperative albumin level ≤3.7 g/dL who received more than the medi...Continue Reading

References

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May 28, 2014·Journal of Surgical Oncology·G Paul WrightMathew H Chung

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Citations

Nov 20, 2020·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Eleni Van DesselArne Neyrinck
Oct 21, 2016·Current Opinion in Anaesthesiology·Chris DurkinJens Lohser
Feb 7, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Ryan S D'SouzaMichael J Brown
Jul 1, 2020·Thoracic Surgery Clinics·Melina Shoni, Gerardo Rodriguez

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