Fluid overload is associated with use of a higher number of antihypertensive drugs in hemodialysis patients.

Hemodialysis International
Jyana G MoraisFabiana B Nerbass

Abstract

Hypertension is multifactorial, highly prevalent in the hemodialysis (HD) population and its adequate control requires, in addition to adequate volume management, often the use of multiple antihypertensive drugs. We aimed to describe the use of antihypertensive agents in a group of HD patients and to evaluate the factors associated with the use of multiple classes (≥3) of antihypertensives. We analyzed the baseline data from the HDFit study. Clinically stable patients with HD vintage between 3 and 24 months without any severe mobility limitation were recruited from sites throughout southern Brazil. Fluid status was measured pre-dialysis with the Body Composition Monitor (BCM; Fresenius, Germany). Fluid overload (FO) was considered when the overhydration index (OH) was greater than 7% of extracellular water (OH/ECW > 7%) and overweight was defined as a body mass index (BMI) greater than 25 kg/m2 . Prescriptions of antihypertensive drugs were obtained from participants' reports and medical records. Logistic regression was employed to determine factors associated with excessive use of antihypertensive medication (≥3 classes). Of 195 studied patients, 171 with complete data were included (70% male, 53 ± 15 years old, 57% of them wi...Continue Reading

References

May 1, 1992·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J S CheighK H Stenzel
Aug 1, 1996·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·S FishbaneJ K Maesaka
Oct 24, 2000·Kidney International·N MazzuchiJ Fernández-Cean
Jan 12, 2001·Journal of the American College of Cardiology·M A WeberD H Smith
Sep 12, 2003·The American Journal of Medicine·Rajiv AgarwalDavid G Warnock
Feb 8, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Atsushi TakedaNoriaki Matsui
Jul 27, 2006·Physiological Measurement·Ulrich M MoisslNigel J Fuller
Jan 10, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Volker WizemannDaniele Marcelli
May 9, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Yi-Wen ChiuRajnish Mehrotra
May 16, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Antonio Alberto LopesEric W Young
Aug 13, 2009·Nephron. Clinical Practice·K IsekiUNKNOWN Committee of Renal Data Registry of the Japanese Society for Dialysis Therapy
Sep 7, 2011·American Journal of Nephrology·Rajiv Agarwal
Oct 13, 2011·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Mihály TapolyaiKlára Berta
Aug 14, 2012·Lancet·Ele Ferrannini, William C Cushman
Nov 28, 2012·Nephron. Clinical Practice·Wang JialinYuan Weijie
Jul 3, 2013·Jornal brasileiro de nefrologia : ʹorgão oficial de Sociedades Brasileira e Latino-Americana de Nefrologia·Fabiana Baggio NerbassHercilio Alexandre da Luz Filho
Nov 14, 2013·BMC Nephrology·Wendy L St PeterUNKNOWN DEcIDE Network Patient Outcomes in End-Stage Renal Disease Study Investigators
Jan 9, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Rajiv AgarwalGetachew G Tegegne
Mar 4, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Mihai OnofriescuAdrian C Covic
Feb 15, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Süreyya YılmazFusun Topcu
Oct 25, 2016·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·George L BakrisMichael A Kraus
Mar 7, 2017·Seminars in Dialysis·Dana C Miskulin, Daniel E Weiner
Apr 18, 2017·Current Vascular Pharmacology·Charalampos N LoutradisPantelis A Sarafidis
Apr 26, 2017·KI Reports·Kamyar Kalantar-ZadehAlpesh N Amin
May 6, 2017·Journal of the American Society of Nephrology : JASN·Carmine ZoccaliStefano Stuard
Sep 25, 2017·Kidney International·Jeffrey M Turner, Aldo J Peixoto
Apr 6, 2018·Current Opinion in Nephrology and Hypertension·Marijke J E Dekker, Jeroen P Kooman
May 3, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Marijke DekkerJeroen Kooman
Aug 17, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Pantelis A SarafidisCarmine Zoccali
Jan 20, 2019·Current Hypertension Reports·Michelle A FravelMony Fraer
Mar 9, 2019·Hemodialysis International·Jenny StenbergHans Furuland

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