Fluid replacement therapy for acute episodes of pain in people with sickle cell disease

The Cochrane Database of Systematic Reviews
Uduak Okomo, Martin M Meremikwu

Abstract

Treating vaso-occlusive painful crises in people with sickle cell disease is complex and requires multiple interventions. Extra fluids are routinely given as adjunct treatment, regardless of the individual's state of hydration with the aim of slowing or stopping the sickling process and thereby alleviating pain. This is an update of a previously published Cochrane Review. To determine the optimal route, quantity and type of fluid replacement for people with sickle cell disease with acute painful crises. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register which comprises of references identified from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings.We also conducted searches of Embase (November 2007), LILACS and www.ClinicalTrials.gov (05 January 2010).Date of most recent search of the Group's Haemoglobinopathies Trials Register: 24 September 2014. Randomised and quasi-randomised controlled trials that compared the administration of supplemental fluids adjunctive to analgesics by any route in people with any type of sickle cell disease during an acute painful episode, under medical supervision (inpatient, day care or com...Continue Reading

Citations

Aug 2, 2018·The Cochrane Database of Systematic Reviews·Patricia M FortinLise J Estcourt
Nov 20, 2019·The Cochrane Database of Systematic Reviews·Tess E CooperPhilip J Wiffen
Aug 2, 2017·The Cochrane Database of Systematic Reviews·Uduak Okomo, Martin M Meremikwu
Sep 26, 2017·Analytical Chemistry·Caroline E Hansen, Wilbur A Lam

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

The Cochrane Database of Systematic Reviews
Uduak Okomo, Martin M Meremikwu
The Cochrane Database of Systematic Reviews
Uduak Okomo, Martin M Meremikwu
The Cochrane Database of Systematic Reviews
Arturo J Martí-Carvajal, Daniel Simancas-Racines
The Cochrane Database of Systematic Reviews
Arturo J Martí-CarvajalJennifer M Knight-Madden
The Cochrane Database of Systematic Reviews
Alison Morton, Susan Wolfe
© 2021 Meta ULC. All rights reserved