Fluorescence imaging of hypochlorous acid and peroxynitrite in vitro and in vivo with emission wavelength beyond 750 nm.

Chemical Communications : Chem Comm
Linfang WangWei Guo

Abstract

A series of near-infrared and photostable Si-oxazine fluorescent dyes was synthesized using a simple three-step procedure, and one of their reduced products, i.e. hydro-Si-oxazine HSiO3, has been utilized to sensitively detect hypochlorous acid and peroxynitrite generation by phagocytes in inflamed and pulmonary fibrosis diseased mice with emission wavelength beyond 750 nm.

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Citations

Jan 2, 2021·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Eli M EspinozaNiren Murthy

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Methods Mentioned

BETA
Fluorescence

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