PMID: 77121Jan 1, 1978Paper

Fluorescence microscopic demonstration of rat mast cells stained with acid dyes

Acta Odontologica Scandinavica
E Hals


The amphoteric acid dyes acid fuchsin, aniline blue WS, azocarmine G, fast green FCF, light green SF and the wholly acid dye thiazine red R were used for fluorochromy of mast cells in sections of formalin or alcohol-formalin fixed rat tongues. By ordinary light the mast cell granules were barely visible. By UV or blue light exitation, however, a selective, secondary fluorescence of varying intensity and contrast against the tissue background manifested itself. By thin layer chromatography each dye revealed 3--7 components. Except for aniline blue WS, the main component(s) of each dye conferred to the granules the same fluorescence as the corresponding whole dye. These results of fluorochromy, together with the findings of methylation and deamination experiments, allowed the assumption that the anionic groups of the dyes were bound to unoccupied basic groups of the mast cell granules.


Nov 1, 1971·Acta Physiologica Scandinavica·U BergqvistB UVNAS
Feb 1, 1969·Archives of Oral Biology·E Hals, K Nielsen
Feb 15, 1964·Experientia·J Adams-RayN A Hillarp
Jan 1, 1966·Zeitschrift für Zellforschung und mikroskopische Anatomie·J Padawer
Oct 1, 1955·Proceedings of the Society for Experimental Biology and Medicine·E P BendittE ROEPER
Jul 1, 1958·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·H PUCHTLER, H ISLER
Jan 1, 1950·Virchows Archiv Für Pathologische Anatomie Und Physiologie Und Für Klinische Medizin·N SCHUMMELFEDER


Apr 1, 1982·Agents and Actions·F Erjavec

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