Fluorescence of Deep Infiltrating Endometriosis During Laparoscopic Surgery: A Preliminary Report on 6 Cases

Surgical Innovation
A De NeefM Fastrez

Abstract

The standard treatment of rectovaginal deep infiltrating endometriosis nodules (RVDIEN) consists in their surgical removal. RVDIEN are anatomically neovascularized. Indocyanine green (ICG) reveals vascularized structures when becoming fluorescent after exposure to near-infrared (NIR) light. This study aims to evaluate if fluorescence-guided surgery can improve the laparoscopic resection of RVDIEN, thus avoiding a rectal perforation. Patients with a symptomatic RVDIEN, scheduled for a laparoscopic rectal shaving, were enrolled in the study. Technically, the RVDIEN was targeted and removed with the help of the NIR imager device Image 1 Spies (Karl Storz GmBH & Co KG, Tuttlingen, Germany) or Visera Elite II (Olympus Europe SE & Co KG, Hamburg, Germany), after an intraoperative, intravenous injection of ICG (0.25 mg/kg). Six patients underwent a fluorescence-guided laparoscopic shaving procedure for the treatment of a nonobstructive RVDIEN. Fluorescence of the RVDIEN was observed in all the patients. In one patient, once the main lesion was removed, the posterior vaginal fornix still appeared fluorescent and was removed. No intraoperative rectal perforation occurred. The postoperative hospital stay was 2 days. No postoperative rect...Continue Reading

References

Aug 29, 2000·Obstetrics and Gynecology·M PossoverA Schneider
May 29, 2003·Gynécologie, obstétrique & fertilité·C ChapronA Fauconnier
Feb 5, 2009·World Journal of Surgery·Vincent AnafJean-Christophe Noel
Feb 5, 2009·Reproductive Biomedicine Online·Christel MeulemanThomas D'Hooghe
Jan 15, 2011·Human Reproduction Update·Christel MeulemanThomas D'Hooghe
May 12, 2012·International Journal of Biomedical Imaging·Jarmo T AlanderPetri Välisuo
Sep 4, 2012·Fertility and Sterility·Philippe R KoninckxJacques Donnez
Apr 2, 2014·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Kenneth A Levey
Aug 12, 2015·Journal of Minimally Invasive Gynecology·Xiaoming GuanBridgett Kelly
Feb 7, 2016·American Journal of Obstetrics and Gynecology·Basma Darwish, Horace Roman
May 24, 2016·American Journal of Obstetrics and Gynecology·Amanda Roman, Vincenzo Berghella
Jul 10, 2016·American Journal of Obstetrics and Gynecology·Horace RomanCarole Abo
Sep 13, 2017·The Lancet. Gastroenterology & Hepatology·Deborah S KellerManish Chand

❮ Previous
Next ❯

Citations

Jan 17, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Franziska SiegenthalerMichael D Mueller
Apr 11, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Luigi C TurcoFrancesco Cosentino
Sep 9, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Manuel M IanieriGiovanni Scambia
Feb 18, 2020·Human Reproduction Open·UNKNOWN Working group of ESGE, ESHRE, and WESRudy Leon De Wilde
Dec 23, 2020·Journal of Minimally Invasive Gynecology·Diego RaimondoRenato Seracchioli
Dec 8, 2021·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Diego RaimondoRenato Seracchioli

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
fluorescence imaging

Software Mentioned

RVDIEN

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.