Fluorescent cell-selective ablation using an adaptive photodynamic method

Chemical Communications : Chem Comm
Yi Rang KimJin Woo Choi

Abstract

Intravital ablation of particular cell populations is necessary to decipher their roles under spatiotemporal conditions. Energy transfer-based photodynamic therapy presented a conditional range for specifically inducing the death of GFP expressing cells, with little effect on normal cells. This novel system enables easy access to the functional study of cells.

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Methods Mentioned

BETA
fluorescence
confocal microscopy
transgenic
transfection

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