Fluorescent nanoparticles as selective Cu(II) sensors

Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology
Rachel Méallet-RenaultChantal Larpent

Abstract

Latex nanoparticles functionalized with cyclam (1,4,8,11-tetraazacyclotetradecane), a copper chelator, have been doped with a fluorescent dye (BODIPY derivative: 4,4-difluoro-8-(2',4',6'-trimethyl)phenyl-2,6-diethyl-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene). The bulky, hydrophobic fluorophore dissolves within the nanoparticles' polymer core up to a concentration of about 88.4 micromol g(-1). At this concentration the fluorescence yield is about 0.80. Adding Cu2+ ions to the solution decreases the fluorescence because of the energy transfer between the dye and the violet copper cyclam complexes. The response is fast: 90% of the quenching occurs within 1 s. The Cu2+ detection threshold is of 1 nanomolar. No interferences were observed with zinc and nickel ions.

References

Nov 1, 1991·Analytical Biochemistry·I D JohnsonR P Haugland
Feb 6, 2002·The Analyst·James P SumnerRaoul Kopelman
Aug 17, 2002·Organic Letters·Bilge Turfan, Engin U Akkaya
Nov 16, 2002·Angewandte Chemie·Steffen Zahn, Timothy M Swager
Jan 9, 2003·Journal of the American Chemical Society·Melanie BradleyFranz Grieser
Aug 9, 2003·Analytical and Bioanalytical Chemistry·Matthew A Cooper
Aug 14, 2003·Chemistry : a European Journal·Christine GozeRaymond Ziessel
Jan 6, 2004·Chemical Communications : Chem Comm·Elena BrasolaUmberto Tonellato
Feb 26, 2004·Journal of the American Chemical Society·Xiangfeng GuoLihua Jia
May 1, 2004·Journal of Chromatography. a·Bin ZhangAndre J Bourque
Sep 29, 2004·Current Opinion in Chemical Biology·Sarah M BuckRaoul Kopelman
Oct 19, 2004·Chemical Communications : Chem Comm·Rachel Meallet-RenaultChantal Larpent
Dec 17, 2004·Journal of the American Chemical Society·Sung Kuk KimJong Seung Kim
Apr 20, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Marco MontaltiGiuseppe Falini
Sep 21, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Maria ArduiniUmberto Tonellato
Nov 18, 2005·Journal of Colloid and Interface Science·Gilles BosmaHenk N W Lekkerkerker

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Citations

Jun 12, 2009·Journal of the American Chemical Society·Mikhail Y BerezinSamuel Achilefu
Jan 26, 2010·Annual Review of Analytical Chemistry·Yong-Eun Koo LeeRaoul Kopelman
Jan 25, 2013·Physical Chemistry Chemical Physics : PCCP·Yuanyuan LiaoRobert B Pansu
Dec 14, 2011·Journal of Immunological Methods·Muki S SheyThomas J Scriba
Jan 6, 2010·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Yong-Eun Koo Lee, Raoul Kopelman
Dec 25, 2010·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·David ZarkowskyMario Roederer
Feb 27, 2010·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Jian ChenShuizhu Wu
Aug 1, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Kateryna TrofymchukAndrey S Klymchenko
Feb 26, 2019·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Chloé GrazonGilles Clavier
Apr 22, 2020·Nature Biomedical Engineering·Jingyi LuanSrikanth Singamaneni
Oct 11, 2007·Chemical Reviews·Aurore Loudet, Kevin Burgess
Oct 27, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Meiyun XuChangmin Yu
Dec 1, 2017·ACS Applied Materials & Interfaces·Andreas ReischAndrey S Klymchenko

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