Fluorescent products and polyunsaturated fatty acids of human testes.

Lipids
R TromblyR K Rhamy

Abstract

Lipid soluble fluorescent pigments from human testis were fractionated by silicic acid column chromatography and silica gel thin layer chromatography. Fluorescence analyses revealed a family of at least 3 compounds with similar fluorescence properties, including excitation and emission maxima, reversible fluorescence quenching by alkaline pH, and fluorescence quenching by heavy metal chelation. These fluorescence characteristics strongly indicated the presence of the conjugated Schiff base fluorophore-N=C-C=C-N-. The chromatographic separations employed enabled a more definitive fluorescence characterization of the lipid soluble pigments known to accumulate late in tissues with age and as a result of lipid peroxidation. Total lipids and fatty acid composition of the total lipids were determined. Polyenoic acids constituted about 40% of the total fatty acids. Histological examination of the tissues revealed some degeneration and edema, but significant spermatogenesis and normal complement of Leydig cells.

References

Oct 1, 1972·CRC Critical Reviews in Toxicology·W S Hartroft, E A Portal
Nov 1, 1974·Journal of Reproduction and Fertility·J G ConiglioR K Rhamy
Apr 1, 1973·Lipids·W R Bidlack, A L Tappel
Mar 1, 1973·Analytical Biochemistry·B L FletcherA L Tappel
Sep 26, 1972·Biochemical and Biophysical Research Communications·M J KornblattR K Murray
Jan 1, 1966·The Biochemical Journal·J T DavisJ G Coniglio

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Citations

Jul 1, 1987·Chemistry and Physics of Lipids·M TsuchidaK Aibara
Jan 1, 1988·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·C Hammer, E Braum
Jan 1, 1987·Critical Reviews in Toxicology·A A Horton, S Fairhurst
Oct 1, 1977·Archives of Biochemistry and Biophysics·H ShimasakiW R Anderson
Apr 1, 1981·American Journal of Obstetrics and Gynecology·T H ParmleyM A Walker
Jul 1, 1987·Chemistry and Physics of Lipids·K Kikugawa, M Beppu

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