Fluorescent sensing of monofunctional platinum species

Chemical Communications : Chem Comm
Clara ShenElizabeth J New

Abstract

We report here FDCPt1, a novel selective fluorescent sensor for monofunctional platinum species. In the presence of such species, FDCPt1 exhibits a 70-fold increase in fluorescence emission, and can be used to monitor the metabolism of Pt(II)-based complexes in colorectal cancer cells. This probe is therefore expected to be valuable in studying changes in Pt coordination and distribution during chemotherapy.

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Citations

Feb 15, 2017·Journal of Medicinal Chemistry·Dorian M Cheff, Matthew D Hall
Feb 24, 2016·Chemical Communications : Chem Comm·Dominic J Hare, Elizabeth J New
Sep 2, 2015·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Justin C JagodinskyMatthew D Hall
Feb 8, 2020·Chemical Communications : Chem Comm·Fung-Kit TangKen Cham-Fai Leung
May 7, 2018·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zelin ChenShuizhu Wu
Feb 26, 2019·Royal Society Open Science·Xingyu QuYang Bai
Sep 28, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Peilian LiuShuizhu Wu

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