Fluorescent ZnII Chemosensor Mediated by a 1,8-Naphthyridine Derivative and It's Photophysical Properties

ChemistryOpen
Wenxiu LuoHaifeng Xiang

Abstract

One of the greatest challenges in using fluorescent chemosensors for highly selective and sensitive transition-metal ions is finding an efficient and simple method for its synthesis. In this study, a highly efficient fluorescence chemosensor for ZnII was developed from N-Boc-L-proline modified 1,8-naphthyridine. The fluorescence intensity of the chemosensor was increased significantly only in the presence of ZnII ion which provided a perceived color change for rapid visual sensing, while other metal ions showed fluorescence quenching or little changes. It was worth noting that the chemosensor L distinguished ZnII from CdII commonly having similar properties. The solvent effect and possible bonding mode for fluorescence enhancement have been also discussed. Results of this study indicated that the Boc-group in l-proline significantly improved the sensitivity and selectivity for ZnII detection performance, as confirmed by comparison experiments and time dependent-density functional theory (TD-DFT) calculations.

References

Aug 6, 1993·Science·T V O'Halloran
Jan 1, 1997·Neurobiology of Disease·M P Cuajungco, G J Lees
Dec 16, 2006·Angewandte Chemie·Matthew L Clarke, José A Fuentes
Aug 14, 2008·Accounts of Chemical Research·Dawei Ma, Qian Cai
Mar 9, 2010·Chemical Reviews·Renatus W SinkeldamYitzhak Tor
Apr 30, 2010·Chemical Society Reviews·Zhaochao XuDavid R Spring
Sep 15, 2012·Chemistry : a European Journal·Jiaoliang WangWeiling Li
Oct 29, 2013·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Hyun KimCheal Kim
Jan 16, 2015·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Nayan RoyT Sanjoy Singh
Sep 4, 2015·Journal of the American Chemical Society·Laura Rodríguez-GarcíaFabian Meemken
Jul 26, 2017·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Wei-Na WuYuan Xue
Aug 19, 2017·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Tanveer A KhanSunil G Naik
Oct 12, 2017·Chemical Society Reviews·Di WuTony D James
Nov 10, 2017·Chemical Society Reviews·Jacek L KolanowskiElizabeth J New

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Methods Mentioned

BETA
column chromatography

Software Mentioned

Gaussian

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