Fluoride concentration in saliva after consumption of a dinner meal prepared with fluoridated salt

Caries Research
J HedmanS Twetman

Abstract

The aim was to determine the fluoride concentration in saliva after intake of a dinner meal prepared with fluoridated salt. The investigation had a randomized cross-over design, and 10 healthy adolescents with natural fluoride content (1.06 ppm) in their drinking water participated after informed consent. After a run-in week, the subjects were served a standardized dinner of spaghetti with minced meat sauce prepared with either fluoridated salt (test arm) or non-fluoridated salt (control arm). The fluoride concentration of the test salt was 250 ppm. Samples of stimulated whole saliva was collected at baseline, directly after eating (0 min) and then after 10, 30 and 180 min. After a 1-week wash-out period, the experimental procedure was repeated with the opposite salt. Fluoride concentration in saliva was measured with a fluoride-specific electrode and the post-ingestion levels were compared with baseline using repeated-measures ANOVA. The mean baseline concentrations were 10.9 and 8.0 microg/l in the test and control arms, respectively. Immediately after the intake, the mean fluoride values increased significantly to 81.6 microg/l in the test arm and to 31.5 microg/l in the control arm (p<0.05). The fluoride levels remained ele...Continue Reading

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Citations

Sep 24, 2009·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·I Espelid
Aug 24, 2007·Caries Research·H Meyer-LueckelA M Kielbassa
Jan 11, 2012·BMC Oral Health·Ella A NaumovaWolfgang H Arnold
Sep 26, 2014·Journal of International Society of Preventive & Community Dentistry·Navin Anand IngleAmit Siwach
Mar 20, 2010·Metabolomics : Official Journal of the Metabolomic Society·Masahiro SugimotoMasaru Tomita
Jun 22, 2013·International Journal of Paediatric Dentistry·Inger WennhallSvante Twetman
Feb 22, 2012·Archives of Oral Biology·E A NaumovaW H Arnold
Apr 14, 2016·Nature Communications·Simone Dussi, Marjolein Dijkstra
Dec 4, 2019·Expert Review of Gastroenterology & Hepatology·Jiaying YuLiyan Liu

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