Fluorine-18 fluorodeoxyglucose positron emission tomography in the follow-up of differentiated thyroid cancer

European Journal of Nuclear Medicine
F GrünwaldH J Biersack

Abstract

Whole-body fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging was performed during the follow-up of 33 patients suffering from differentiated thyroid cancer. Among them there were 26 patients with papillary and seven with follicular tumours. Primary tumour stage (pT) was pT1 in six cases, pT2 in eight cases, pT3 in three cases and pT4 in 14 cases. FDG PET was normal in 18 patients. In three patients a slightly increased metabolism was observed in the thyroid bed, assumed to be related to remnant tissue. In one case local recurrence, in ten cases lymph node metastases (one false-positive, caused by sarcoidosis) and in three cases distant metastases were found with FDG PET. In comparison with whole-body scintigraphy using iodine-131 (WBS) there were a lot of discrepancies in imaging results. Whereas three patients had distant metastases (proven with 131I) and a negative FDG PET, in four cases 131I-negative lymph node metastases were detectable with PET. Even in the patients with concordant "staging", differences between 131I and FDG were observed as to the exact lesion localization. Therefore, a coexistence of 131I-positive/FDG-negative, 131I-negative/FDG-positive and 131I-positive/FDG-positive malign...Continue Reading

References

Dec 1, 1991·Clinical Endocrinology·E G Black, M C Sheppard
Jan 1, 1991·European Journal of Nuclear Medicine·H J Biersack, A Hotze
Jan 1, 1988·European Journal of Nuclear Medicine·H JoensuuP J Klemi
Jul 1, 1994·The Journal of Clinical Endocrinology and Metabolism·M OzataL J DeGroot
Jan 1, 1993·Thyroid : Official Journal of the American Thyroid Association·L P Adler, A D Bloom

❮ Previous
Next ❯

Citations

Dec 1, 1996·European Journal of Nuclear Medicine·P RigoJ Foidart-Willems
Feb 6, 2007·European Journal of Nuclear Medicine and Molecular Imaging·Marc-André FortinHans Lundqvist
Jul 3, 2004·European Radiology·L S FreudenbergW Brandau
Oct 1, 2003·Clinical Positron Imaging : Official Journal of the Institute for Clinical P.E.T·Hossein Jadvar, Alan J. Fischman
Mar 28, 2002·Thyroid : Official Journal of the American Thyroid Association·Michail PlotkinHans-Wilhelm Müller-Gärtner
Aug 10, 1999·Clinical Nuclear Medicine·H AlibazogluA Ali
Feb 24, 2001·Nuclear Medicine Communications·M DietleinH Schicha
Jun 5, 2001·Nuclear Medicine Communications·I R McDougallG M Segall
Nov 30, 2006·Current Opinion in Oncology·Elizabeth Holt
Jun 6, 2008·Nuclear Medicine Communications·Marc D ZuijdwijkWim J G Oyen
Aug 22, 2007·Clinical Nuclear Medicine·Andrei IagaruI Ross McDougall
Jul 23, 2014·Best Practice & Research. Clinical Endocrinology & Metabolism·Luca GiovanellaGiorgio Treglia
Sep 27, 2003·The British Journal of Radiology·N KhanK Endo
May 1, 2009·Expert Opinion on Medical Diagnostics·Muammer UrhanAbass Alavi
Dec 2, 2008·Best Practice & Research. Clinical Endocrinology & Metabolism·Richard J Robbins, Steven M Larson
Dec 2, 2008·Otolaryngologic Clinics of North America·Michele E Brenner, Heather A Jacene
Nov 21, 2007·Clinical Breast Cancer·Sara M TolaneyEric P Winer
Jun 12, 2008·Seminars in Oncology·Rebecca L Brown
Jan 8, 2008·Surgical Oncology Clinics of North America·Timothy A ManzonePrakash Seshadri
Feb 24, 2011·ANZ Journal of Surgery·Ivan Ho ShonPeter Campbell

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.