Fluorogen-activating proteins as biosensors of cell-surface proteins in living cells.

Cytometry. Part a : the Journal of the International Society for Analytical Cytology
John HolleranJonathan Jarvik

Abstract

This study explores the general utility of a new class of biosensor that allows one to selectively visualize molecules of a chosen membrane protein that are at the cell surface. These biosensors make use of recently described bipartite fluoromodules comprised of a fluorogen-activating protein (FAP) and a small molecule (fluorogen) whose fluorescence increases dramatically when noncovalently bound by the FAP (Szent-Gyorgyi et al., Nat Biotechnol 2010;00:000-000).

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Citations

Dec 21, 2012·Journal of the American Chemical Society·Nathaniel I ShankBruce A Armitage
Jan 27, 2016·Journal of Molecular Biology·Marco SchützAndreas Plückthun
Mar 1, 2012·Methods : a Companion to Methods in Enzymology·Matthew J SaundersAlan S Waggoner
Jan 11, 2013·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Yang WuLarry A Sklar
Oct 15, 2013·Biotechnology and Bioengineering·Eugenio GalloJonathan Jarvik
Apr 7, 2015·Protein Engineering, Design & Selection : PEDS·Eugenio GalloJonathan W Jarvik
Feb 14, 2015·Organic & Biomolecular Chemistry·Ha H PhamBruce A Armitage
Mar 26, 2015·Journal of Biomolecular Screening·Bruce S Edwards, Larry A Sklar
Apr 18, 2017·Bioconjugate Chemistry·Daniel S AckermanJonathan W Jarvik
Jul 26, 2018·American Journal of Physiology. Renal Physiology·Ankita Bachhawat JaykumarPablo A Ortiz
Mar 7, 2015·Cell and Tissue Research·Qi Yan, Marcel P Bruchez
Feb 23, 2020·Traffic·Lydia A Perkins, Marcel P Bruchez
Apr 14, 2018·Scientific Reports·Alexander BraunKenneth A Myers
Sep 13, 2018·Molecular Biology of the Cell·Anita Emmerstorfer-AugustinJeremy Thorner
Jul 13, 2017·International Journal of Molecular Sciences·Chenge LiArnaud Gautier
Dec 11, 2019·International Journal of Molecular Sciences·Tiphaine Péresse, Arnaud Gautier
Apr 11, 2013·Journal of Cell Science·John P HolleranSimon C Watkins
May 24, 2018·Bioconjugate Chemistry·Chenge LiArnaud Gautier
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Dec 24, 2014·Journal of the American Chemical Society·Ipek YapiciBabak Borhan
Jul 10, 2014·BMC Cell Biology·Sandeep SalipalliJürgen Borlak

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