Fluorometric determination of serum and urinary aluminium with 8-quinolinol by kinetic-differentiation-mode micellar chromatography

Journal of Chromatography. a
M SatoT Yotsuyanagi

Abstract

A new fluorometric method has been developed for the determination of aluminium with 8-quinolinol by kinetic-differentiation-mode micellar chromatography. The proposed method enabled the determination of aluminium down to 1 microgram/l in human serum and urine without preliminary deproteinization. The most remarkable point of this method is that only aluminium ion selectively responds among metal ions. The complex formation of aluminium in serum with 8-quinolinol was completed within a few minutes at room temperature. The serum matrix and aluminium chelate were separated on a reversed-phase column with an eluent containing acetonitrile, sodium dodecylsulfate, and Triton X-100, and aluminium chelate was detected at Ex 370 nm, Em 504 nm. The values obtained by this method were in good agreement with those of Zeeman graphite-furnace atomic absorption spectrometry. The proposed method will provide a simple and rapid technique for the determination aluminium in medical fields.

References

Jan 22, 1976·The New England Journal of Medicine·A C AlfreyW D Kaehny
Oct 31, 1986·Clinica Chimica Acta; International Journal of Clinical Chemistry·F A de Wolff, G B van der Voet
Jan 28, 1994·Biochemical and Biophysical Research Communications·M KawaharaY Kuroda

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Citations

Jun 12, 2003·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Koji KashimuraShuzo Matsubara
Aug 5, 2009·Chemical Communications : Chem Comm·Jong Seung KimJacques Vicens
May 11, 2002·The Tohoku Journal of Experimental Medicine·Junko ChibaSeizaburo Sakamoto
May 24, 2006·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·M-S Pyun, S Shin

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