Fluvirucin B6, a new macrolactam isolated from a marine-derived actinomycete of the genus Nocardiopsis

The Journal of Antibiotics
Alain S LeutouWilliam Fenical

Abstract

A new 14-membered macrolactam natural product, fluvirucin B6 (1), was isolated from a marine-derived actinomycete, Nocardiopsis sp. CNQ-115, via HPLC-UV guided isolation. The chemical structure of 1 was elucidated by 1D and 2D NMR spectroscopic data analysis. Compound 1 showed a weak activity against Gram-positive bacteria, whereas it was inactive against Gram-negative bacteria.

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Citations

Feb 7, 2020·Natural Product Reports·Anthony R CarrollMichèle R Prinsep
May 2, 2018·Marine Drugs·Alyaa Hatem IbrahimUsama Ramadan Abdelmohsen
Jul 28, 2020·The Journal of Antibiotics·Hiroshi Tomoda, James B McAlpine
Jul 22, 2020·Archives of Pharmacal Research·Cong WangShugeng Cao
Feb 3, 2021·Microbiological Research·Polpass Arul JoseBhavanath Jha
Apr 26, 2019·Journal of Natural Products·Omar MessaoudiJoachim Wink

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Methods Mentioned

BETA
NMR
X-ray

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