PMID: 9161652May 1, 1997Paper

Fluvoxamine for stereotypic behavior in patients with dementia

The Annals of Pharmacotherapy
B Trappler, L M Vinuela

Abstract

To describe the effects of treatment with the selective serotonin reuptake inhibitor fluvoxamine on three patients with advanced dementia who developed a stereotypic movement disorder. Three patients in a skilled nursing facility were referred by their primary physicians for psychiatric consultation to assist with the management of stereotypic behaviors. The patients received a standard medical, neurologic, and psychiatric workup for dementia. Two of the patients were diagnosed with dementia of the Alzheimer type and the other patient was diagnosed with vascular dementia. All three patients were started on fluvoxamine 25 mg/d; behaviors were monitored daily by the nursing staff and their primary care physicians and weekly by their psychiatrist using the Abnormal Involuntary Movement Scales. The dosage was titrated upward weekly to a maximum dosage of 150 mg/d. Two patients showed complete resolution of their stereotypic behaviors by week 6. The third patient showed noticeable improvement with some residual movements after 8 weeks of treatment. Fluvoxamine appeared effective in the control of stereotypic behaviors in three patients with advanced dementia.

References

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Jul 1, 1996·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Brian Trappler, Carl I Cohen

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Citations

Mar 29, 2006·Journal of Child Neurology·Jonathan M MillerH Richard Waranch
Apr 13, 2007·Fukushima Journal of Medical Science·Masatake KuritaNorimichi Nakahata
Mar 21, 2013·American Journal of Alzheimer's Disease and Other Dementias·Gabriele CiprianiClaudio Lucetti
Sep 23, 2000·International Journal of Psychiatry in Medicine·J P HwangJ F Lirng

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