Focal early stage cancer in ampullary adenoma: surgery or endoscopic papillectomy?

Gastrointestinal Endoscopy
Soon Man YoonSung Koo Lee


Recently, the evidence has been accumulating that endoscopic resection may be curative in treating ampullary adenoma that contains high-grade intraepithelial neoplasia/in situ tumor (HGIN/Tis). However, there are only anecdotal reports of endoscopic management of "focal" T1 ampullary cancer (T1 cancer), and radical surgery is still considered the only accepted treatment modality. To assess the possibility of endoscopic papillectomy as an alternative to radical surgery for the treatment of ampullary adenoma with HGIN/Tis or focal T1 cancer. Retrospective evaluation of case series of our hospital from 1996 to 2006. Tertiary-care university teaching hospital. Twenty-three patients who had HGIN/Tis or focal T1 cancer in ampullary adenoma resected by endoscopic papillectomy and 60 patients who initially underwent radical surgery for HGIN/Tis or T1 cancer of the ampulla of Vater. "Focal" was defined as a lesion involving only mucosa, with a size less than a fourth the diameter of main adenoma. Review of medical records and analysis of surgically or endoscopically resected specimens of ampullary tumors. Locoregional extension and follow-up data. Patients with HGIN/Tis of the ampulla of Vater had no lymphovascular invasion or lymph-nod...Continue Reading


May 1, 1997·World Journal of Surgery·T C BöttgerT Junginger
May 19, 2000·Yonsei Medical Journal·S W ParkI S Park
Jun 8, 2002·World Journal of Surgery·Claus-Dieter HeideckeJörg-Rüdiger Siewert
Dec 5, 2003·Annals of Surgical Oncology·Takeshi TodorokiHideto Takahashi
Feb 28, 2004·Gastrointestinal Endoscopy Clinics of North America·John A Martin, Gregory B Haber
Sep 16, 2004·Journal of Hepato-biliary-pancreatic Surgery·Daniel ParamythiotisMarkus W Büchler
Sep 16, 2004·Journal of Hepato-biliary-pancreatic Surgery·Jean P ChartonHorst Neuhaus
Mar 10, 2005·Surgical Innovation·Tin C Tran, Gary C Vitale
Sep 28, 2005·Gastrointestinal Endoscopy·Sabine BohnackerNib Soehendra
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Jan 24, 2006·Endoscopy·P NevesD Freitas
May 3, 2006·Gastrointestinal Endoscopy·Sun-Young LeeJong Chul Rhee
May 3, 2006·Gastrointestinal Endoscopy·Stefan SeewaldNib Soehendra
Jun 13, 2006·Endoscopy·S BohnackerD A Howell

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