PMID: 11309038Apr 20, 2001Paper

Focal facial dermal dysplasia or aplasia cutis congenita: a case with a hair collar

The Australasian Journal of Dermatology
J M Wells, D Weedon

Abstract

Aplasia cutis congenita describes localized defects of skin that may have many causes. A 6-month-old male presented with bilateral atrophic patches on his cheeks distributed along a line from the preauricular area to the angle of the mouth. They had been present since birth. He had no other abnormalities detectable on examination and no family history of similar lesions. A distinct collar of long pale hairs surrounded the lesions, especially the largest one. Histology showed changes consistent with aplasia cutis congenita or focal facial dermal dysplasia. We propose our patient's lesions may be the result of failure of ectodermal fusion over embryological closure lines. This may be a distinct subgroup of atrophic facial lesions.

References

Jul 1, 1979·Pathology·D Weedon, G Ritchie
Jul 1, 1975·Pathology·D Weedon, J F Kerr
Oct 1, 1992·Journal of the American Academy of Dermatology·D C Kowalski, N A Fenske
Aug 1, 1991·Journal of the American Academy of Dermatology·V Di LerniaA Patrizi
May 1, 1988·Journal of the American Academy of Dermatology·M L MagidN B Esterly
Apr 1, 1986·Journal of the American Academy of Dermatology·I J Frieden
Oct 1, 1974·Archives of Dermatology·R I RudolphJ J Leyden
May 1, 1971·The British Journal of Dermatology·N E Jensen
May 1, 1994·The British Journal of Dermatology·K A Ward, C Moss
Oct 1, 1996·The British Journal of Dermatology·Y K TayW L Weston
Jan 8, 1998·Archives of Dermatology·B A DroletN B Esterly
Feb 17, 1999·The British Journal of Dermatology·N Stone, S Burge

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Citations

Nov 20, 2012·Human Molecular Genetics·Anne M SlavotinekRobert J Desnick
Jun 26, 2008·Pediatric Dermatology·Michael S KrathenGlen H Crawford
Jan 16, 2014·Hand : Official Journal of the American Association for Hand Surgery·Marisa Cabrera GonzálezAntonia González Enseñat
Oct 31, 2012·Pediatric Dermatology·Carrie C CoughlinDavid R Berk
Nov 14, 2006·Journal of the American Academy of Dermatology·Arash IzadpanahLynne M Bird
Mar 22, 2019·Pediatric Dermatology·Marieke DonnéDirk Van Gysel
Dec 22, 2017·Journal of Human Genetics·Beom Hee LeeRobert J Desnick

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