Focal putamen lesions impair learning in rule-based, but not information-integration categorization tasks

Neuropsychologia
Shawn W EllRichard B Ivry

Abstract

Previous research on the role of the basal ganglia in category learning has focused on patients with Parkinson's and Huntington's disease, neurodegenerative diseases frequently accompanied by additional cortical pathology. The goal of the present study was to extend this work to patients with basal ganglia lesions due to stroke, asking if similar changes in performance would be observed in patients with more focal pathology. Patients with basal ganglia lesions centered in the putamen (6 left side, 1 right side) were tested on rule-based and information-integration visual categorization tasks. In rule-based tasks, it is assumed that participants can learn the category structures through an explicit reasoning process. In information-integration tasks, optimal performance requires the integration of information from two or more stimulus components, and participants are typically unaware of the category rules. Consistent with previous studies involving patients with degenerative disorders of the basal ganglia, the stroke patients were impaired on the rule-based task, and quantitative, model-based analyses indicate that this deficit was due to the inefficient application of decision strategies. In contrast, the patients were unimpai...Continue Reading

References

Jan 1, 1988·Journal of Experimental Psychology. Learning, Memory, and Cognition·F G Ashby, R E Gott
Apr 1, 1988·Brain : a Journal of Neurology·R G Brown, C D Marsden
May 1, 1984·Journal of Neurology, Neurosurgery, and Psychiatry·A R CoolsH J Berger
Mar 1, 1982·Journal of Dentistry·J Wickens
Jan 1, 1993·Perception & Psychophysics·W T Maddox, F G Ashby
Sep 6, 1996·Science·B J KnowltonL R Squire
Sep 1, 1996·Nursing Research·C T Beck
Jan 1, 1997·Spatial Vision·D H Brainard
Aug 11, 1998·Psychological Review·F G AshbyE M Waldron
Apr 11, 2001·Journal of Experimental Psychology. General·F G AshbyA Berkman
Apr 20, 2001·Journal of the International Neuropsychological Society : JINS·E R SowellT L Jernigan
Apr 27, 2001·Trends in Cognitive Sciences·F G. Ashby, S W. Ell
Sep 25, 2001·Behavioural Neurology·Chris Rorden, Matthew Brett
Dec 6, 2001·Nature·R A PoldrackM A Gluck
Apr 24, 2002·Journal of Cognitive Neuroscience·K WittG Deuschl
Aug 30, 2002·Psychonomic Bulletin & Review·F G Ashby, E M Waldron
Nov 29, 2002·Cognitive, Affective & Behavioral Neuroscience·Carol A Seger, Corinna M Cincotta
Aug 20, 2003·Journal of Experimental Psychology. Learning, Memory, and Cognition·W Todd MaddoxCorey J Bohil
Sep 23, 2003·Brain Research. Brain Research Reviews·Szabolcs Kéri
Jan 6, 2004·Memory & Cognition·F Gregory AshbyElliott M Waldron
Jan 20, 2004·Journal of Chemical Neuroanatomy·Suzanne N Haber
Jan 23, 2004·Journal of Experimental Psychology. Learning, Memory, and Cognition·W Todd MaddoxA David Ing
Apr 29, 2004·Behavioral Neuroscience·Teena D MoodyBarbara J Knowlton
May 26, 2004·Behavioural Processes·W Todd Maddox, F Gregory Ashby
Nov 13, 2004·Behavioral and Cognitive Neuroscience Reviews·F Gregory Ashby, Brian J Spiering
Jan 22, 2005·Brain : a Journal of Neurology·C E LongworthL K Tyler
Jan 27, 2005·Neuroreport·J Vincent FiloteoMartin P Paulus
Feb 16, 2005·Annual Review of Psychology·F Gregory Ashby, W Todd Maddox
Mar 1, 2005·Psychonomic Bulletin & Review·W Todd MaddoxA David Ing
Mar 17, 2005·Neuropsychology·J Vincent FiloteoDavid D Song
Mar 25, 2005·Brain : a Journal of Neurology·Marc TeichmannAnne-Catherine Bachoud-Lévi
Apr 27, 2005·Cognitive, Affective & Behavioral Neuroscience·Silvia A Bunge

❮ Previous
Next ❯

Citations

Oct 6, 2010·Proceedings of the National Academy of Sciences of the United States of America·Bradley Voytek, Robert T Knight
Jan 31, 2012·Brain, Behavior and Evolution·Timothy C RothVladimir V Pravosudov
May 30, 2014·American Journal on Intellectual and Developmental Disabilities·B Allyson PhillipsMark R Klinger
Dec 3, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Sébastien HélieF Gregory Ashby
Dec 17, 2014·Journal of Neuroscience Research·Mary A WooRajesh Kumar
May 27, 2011·Journal of the Neurological Sciences·Rajesh KumarRonald M Harper
Jun 16, 2010·Neuropsychologia·W Todd MaddoxDavid M Schnyer
May 9, 2009·NeuroImage·Eugene TunikScott T Grafton
Jul 20, 2014·NeuroImage·Nole M HiebertPenny A MacDonald
Aug 1, 2009·Neuropsychologia·David M SchnyerMieke Verfaellie
Feb 5, 2008·Neuropsychologia·Henry W ChaseTrevor W Robbins
Oct 12, 2014·European Child & Adolescent Psychiatry·Astrid BjørnebekkKristine B Walhovd
Nov 5, 2016·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jasper WinkelBirte U Forstmann
Oct 8, 2015·Journal of Alzheimer's Disease : JAD·Sandra E LehLars Michels
Nov 14, 2015·Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih·Xiang QuanShou-Yuan Tian
Nov 26, 2016·Journal of Psycholinguistic Research·Barbara GawdaTomasz Wolak
Mar 25, 2019·Translational Psychiatry·Mary MuffordUNKNOWN Psychiatric Genomics Consortium - Tourette Syndrome working group
Jan 20, 2021·Psychonomic Bulletin & Review·Gregory I Hughes, Ayanna K Thomas

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Basal ganglia in Parkinson's disease (MDS)

The basal ganglia is comprised of the neostriatum, the external and internal pallidal segments, the subthalamic nucleus, the substantia nigra pars reticulata, and the pars compacta of the substantia nigra. The basal ganglia circuitry is responsible for the correct execution of voluntary movements and is implicated in Parkinson's disease. Here is the latest research investigating the basal ganglia in Parkinson's disease.