Focal sensory-motor status epilepticus in multiple sclerosis due to a new cortical lesion. An EEG-fMRI co-registration study

Seizure : the Journal of the British Epilepsy Association
Elisa GaspariniStefano Meletti

Abstract

A case of focal inferior limb sensory-motor status epilepticus as the only manifestation of a multiple sclerosis (MS) relapse is described. To obtain evidence of the relationship between the seizures, the cortical plaque and the left foot motor area, an EEG-fMRI co-registration study was undertaken demonstrating that seizure-related BOLD signal substantially overlapped with the inflammatory lesion involving the foot sensory-motor cortex. Seizures did not respond to intravenous anti-epileptic drugs (AEDs) but were controlled by steroid therapy.

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Citations

Oct 2, 2012·QJM : Monthly Journal of the Association of Physicians·J Ganesalingam, O Malik
Nov 23, 2017·Clinical EEG and Neuroscience·Murat Mert Atmaca, Candan Gurses

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