Focal sonographic periventricular pattern associated with mild ventriculomegaly in foetal cytomegalic infection revealing cytomegalic encephalitis in the third trimester of pregnancy

Prenatal Diagnosis
Laurent GuibaudFrançois Golfier

Abstract

To report focal sonographic periventricular pattern related to residual germinal matrix lesions in foetal cytomegalic infection in association with mild ventriculomegaly seen during the third trimester of pregnancy correlating with neuropathological findings of encephalitis. We reviewed prenatal cerebral sonographic examination performed in three patients, during the third trimester of pregnancy, looking for either late 'isolated' ventriculomegaly (n = 2) or sonographic follow-up of cerebral structures following a known primary CMV infection in the early stage of pregnancy (n = 1). In cases of isolated ventriculomegaly, serological examination identified prenatal CMV infection. Magnetic resonance imaging (MRI) was performed in all cases. Imaging findings were compared with those following neuropathological examination. In all cases, ultrasound examination revealed an abnormal focal symmetrical bilateral periventricular pattern on the mid-lateral border of the lateral ventricles, including a mainly hyperechogenic lesion containing a few microcysts (case 1), a mixture of echogenic tissue and cysts (case 2) and mainly cystic areas (case 3). No alteration of cephalic biometry was noted. Neuropathological examination correlated thes...Continue Reading

Citations

May 21, 2011·Pediatric Radiology·Renzo ManaraEzia Maria Ruga
Oct 22, 2008·Obstetrical & Gynecological Survey·Lourens R PistoriusDaniela Prayer
Jan 17, 2012·Paediatric Drugs·Luc De CatteFilip Claus
Nov 9, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Kathleen R FinkSumit Pruthi
Feb 25, 2011·Journal de gynécologie, obstétrique et biologie de la reproduction·A-G CordierO Picone
Feb 17, 2015·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·H EstebanC Garel
Sep 9, 2006·Seminars in Fetal & Neonatal Medicine·Johanna I P de Vries
Jan 18, 2006·European Journal of Radiology·Daniela PrayerMartin Langer
Oct 10, 2014·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Laurent Guibaud, Audrey Lacalm
Apr 25, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Maria-Teresa GervasiGiorgio Palù
Jan 15, 2008·American Journal of Obstetrics and Gynecology·Brunella GuerraNicola Rizzo
Nov 23, 2010·Fetal Diagnosis and Therapy·Gustavo MalingerTally Lerman-Sagie
Apr 18, 2008·Fetal Diagnosis and Therapy·Theera TongsongPodjanee Phadungkiatwattna

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