Focus on clozapine

Current Medical Research and Opinion
M Naheed, B Green

Abstract

Clozapine is a dibenzodiazepine derivative and a truly atypical anti-psychotic. Its therapeutic effects are probably mediated by dopaminergic and serotonergic activity. Although it appears to be the most effective antipsychotic drug for treatment-resistant schizophrenia, its general use is limited because of the risk of agranulocytosis.

Citations

Apr 2, 2013·Archives of Pharmacal Research·Eun Ji ParkDong Hee Na
Mar 12, 2004·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Nadeem H BhanjiHoward C Margolese
Mar 24, 2009·Analytical Chemistry·Oscar YanesGary Siuzdak
Sep 21, 2013·ACS Chemical Neuroscience·Cody J Wenthur, Craig W Lindsley
Apr 28, 2007·The Australian and New Zealand Journal of Psychiatry·Florence Levy
Sep 2, 2008·Expert Opinion on Drug Safety·Pietro GareriGiovambattista De Sarro
Apr 2, 2011·Human Psychopharmacology·Francesco Saverio BersaniMassimo Biondi
Dec 19, 2015·Proteomics. Clinical Applications·Juliana S CassoliDaniel Martins-de-Souza
Jan 15, 2015·Pharmacology & Therapeutics·William T O'Connor, Sean D O'Shea
May 18, 2010·Molecular and Biochemical Parasitology·Vijayaraghava T S RaoSean G Forrester
Nov 21, 2013·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Michael C DavisStephen R Marder
Jul 24, 2018·Journal of Toxicology and Environmental Health. Part a·Aleksandra Nikolić-KokićČedo Miljević

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