Foetal alcohol syndrome: a cephalometric analysis of patients and controls

European Journal of Orthodontics
Sudeshni NaidooCarl Lombard

Abstract

Foetal alcohol syndrome (FAS) consists of multi-system abnormalities and is caused by the excessive intake of alcohol during pregnancy. The teratogenic effect of alcohol on the human foetus has now been established beyond reasonable doubt and FAS is the most important human teratogenic condition known today. The purpose of this study was to analyse the craniofacial parameters of children with FAS and compare them with matched controls. Ninety children diagnosed with FAS (45 males, 45 females) and 90 controls were matched for age, gender, and social class. The mean age of the FAS children was 8.9 years with the controls slightly older at 9.1 years. This age difference was not significant (P = 0.34). A standard lateral cephalometric radiograph of each subject was taken. The radiographs were digitized for 20 linear and 17 angular measurements. These 37 variables were formulated to assess the size, shape, and relative position of three craniofacial complexes: (1) the cranial base, (2) midface, and (3) mandible. In addition, nine variables were computed to compare the soft tissue profiles. The study showed that measurements related to face height and mandibular size appear to be the most important features when distinguishing FAS ch...Continue Reading

Citations

Jul 12, 2008·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Naif A BindayelEmad Al-Farra
Jan 27, 2010·American Journal of Medical Genetics. Part a·Tania S Douglas, Tinashe E M Mutsvangwa
Oct 4, 2018·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Moritz Blanck-LubarschAriane Hohoff
Dec 17, 2009·American Journal of Medical Genetics. Part a·Tinashe E M MutsvangwaTania S Douglas
Jun 22, 2017·Birth Defects Research·Rachel StadelmaierLewis B Holmes
Jun 3, 2016·American Journal of Medical Genetics. Part a·Katherine AbellOmar Abdul-Rahman
Oct 21, 2016·Alcoholism, Clinical and Experimental Research·Annika C MontagUNKNOWN CIFASD

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