PMID: 702015Aug 1, 1978Paper

Foetal and maternal plasma concentrations of 13, 14-dihydro-15-oxo-prostaglandin F in the mare during late pregnancy and at parturition

The Journal of Endocrinology
R J BarnesM Silver

Abstract

The concentrations of 13, 14-dihydro-15-oxo-prostaglandin F(PGFM), the stable metabolite of prostaglandin F, were measured in the plasma of catheterized mares and foetuses and non-catheterized thoroughbred mares and ponies during the last months of gestation. The plasma concentration of PGFM increased gradually towards term in all groups of animals. During the operation for insertion of catheters, maternal and foetal concentrations of PGFM were high, but the values fell to basal levels 24--48 h after the operation. It was found the preoperative starvation (24 h) led to a rise in the concentration of PGFM in the maternal plasma. The raised concentrations of PGFM during the operation were associated with low progestogen and high oestrogen concentrations in umbilical venous plasma. The subsequent survival period of the catheterized foal was inversely related to the maximum concentration of PGFM were studied during normal parturition in thoroughbred mares, during oxytocin-induced delivery in non-catheterized ponies and during premature delivery or abortion in the catheterized animals. The greatest increase in the concentration of PGFM was seen in the thoroughbred animals during second-stage labour; oxytocin also resulted in a very ...Continue Reading

Citations

Nov 1, 1993·Equine Veterinary Journal·K J Boening, I P Leendertse
May 19, 2012·Equine Veterinary Journal. Supplement·J C Ousey, A L Fowden
Jul 1, 1984·Equine Veterinary Journal·A L FowdenM Silver
Jul 1, 1984·Equine Veterinary Journal·J C OuseyM Silver
Jul 1, 1984·Equine Veterinary Journal·A L FowdenP D Rossdale
Apr 1, 1980·Equine Veterinary Journal·R L Pashen
May 24, 2011·Reproduction in Domestic Animals = Zuchthygiene·S PanzaniM C Veronesi
Jun 1, 1997·Equine Veterinary Journal. Supplement·P M Taylor
Nov 1, 1980·The Veterinary Clinics of North America. Large Animal Practice·R B Hillman, S A Lesser

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