PMID: 7082621May 1, 1982Paper

Foetal mortality in moderately zinc-deficient rats is strictly related to the process of parturition: effect of maternal essential fatty acid supplementation

The British Journal of Nutrition
S C Cunnane

Abstract

1. Although disrupted parturition and high foetal losses have previously been reported in pregnant rats maintained on zinc-deficient diets this is the first report to differentiate between the effects of reduced Zn intake and the effects of reduced food intake on the outcome of pregnancy in the rat. 2. Rats maintained on a 0.5 mg Zn/kg diet for the last 7 d of gestation or on a 5 mg Zn/kg diet throughout gestation did not consume significantly less food than rats given 10 or 20 mg Zn/kg diets except during the last 2d of gestation. Pair-feeding of Zn-adequate rats (20 mg/kg) to those given low-Zn diets for the last 2 d of gestation did not affect the outcome of pregnancy in these rats. 3. In the rats maintained throughout gestation on 5 mg Zn/kg or on 0.5 mg Zn/kg in the last 7 d of gestation, parturition onset and duration were not significantly altered. Foetal survival was very significantly reduced but only from day 22 onwards; before the onset of parturition, foetal survival was not significantly affected by Zn deficiency during gestation. 4. Subcutaneous injection of evening primrose (Oenothera biennis) oil into rats throughout gestation enhanced foetal and neonatal survival in rats given 5 mg Zn/kg but reduced foetal surv...Continue Reading

References

Apr 1, 1979·Journal of Dairy Science·R L Kincaid, J D Cronrath
Aug 1, 1978·British Journal of Obstetrics and Gynaecology·M C ElphickD Hull
Jul 1, 1977·The Journal of Nutrition·B L O'DellPhilip G Reeves
Sep 20, 1973·The American Journal of Cardiology·J F Williams
Nov 9, 1972·The New England Journal of Medicine·P Felig
Dec 1, 1970·The British Journal of Nutrition·R B Williams, C F Mills
Jul 1, 1968·The American Journal of Physiology·J Apgar
Dec 1, 1981·American Journal of Surgery·J M Holman, D Albo
Sep 1, 1980·Proceedings of the Society for Experimental Biology and Medicine·S C Cunnane, D F Horrobin

Citations

Jul 1, 1984·The British Journal of Nutrition·S J Fairweather-TaitC M Williams
Mar 1, 1988·The British Journal of Nutrition·N J FullerC J Bates
Jun 1, 1983·The Proceedings of the Nutrition Society·W M Leat
Jan 1, 1985·Acta Paediatrica Scandinavica. Supplement·I Villa Elízaga, R M da Cunha Ferreira
Feb 24, 2006·Nutrition Reviews·Dheeraj Shah, H P S Sachdev

Related Concepts

Ingestion
Fatty Acids, Essential
Fetal Mummification
Labor (Childbirth)
Maternal-Fetal Exchange
August Rats
Zinc

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