PMID: 9446844Mar 7, 1998Paper

Folate catabolism in pregnant and nonpregnant women with controlled folate intakes

The Journal of Nutrition
Marie A CaudillL B Bailey

Abstract

Measurement of the urinary folate catabolites, para-aminobenzoylglutamate (pABG) and the more predominant acetylated form, acetamidobenzoylglutamate (apABG), has been used to assess folate requirements in both pregnant and nonpregnant women. Folate catabolite excretion has been reported to be significantly higher in pregnant women (second trimester) compared with nonpregnant controls. The primary goals of this study were to determine if pregnant women in a controlled metabolic study excreted higher quantities of urinary folate catabolites than nonpregnant controls and if catabolite excretion was influenced by folate intake. We evaluated the effect of gestation and folate intake on the urinary excretion of apABG and pABG in pregnant women (n = 12; wk 14-26 gestation) and nonpregnant controls (n = 12) assigned to consume folate levels approximating the current (400 microg/d) and previous (800 microg/d) RDA. Subjects were fed a controlled diet containing 120 microg folate/d and either 330 or 730 microg synthetic folic acid/d. In contrast to previously reported data, no differences in mean folate catabolite excretion were detected between pregnant and nonpregnant subjects. Catabolite excretion (pABG + apABG) decreased significantly...Continue Reading

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Citations

Aug 18, 2001·The British Journal of Nutrition·K Krishnaswamy, K Madhavan Nair
Dec 1, 2001·Nutrition Research Reviews·I A BrouwerR P Steegers-Theunissen
Apr 16, 1999·The Journal of Nutrition·L B Bailey, J F Gregory
Jul 27, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·L B BaileyA Cruz
May 11, 2006·The American Journal of Clinical Nutrition·Tsunenobu Tamura, Mary Frances Picciano
May 24, 2003·The Journal of Biological Chemistry·Montserrat C AngueraPatrick J Stover
Jul 23, 2005·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Robert W PowersJames M Roberts
Sep 18, 2008·Journal of Nutritional Science and Vitaminology·Hee-Ah Kim, Hyeon-Sook Lim
Apr 2, 2013·The Cochrane Database of Systematic Reviews·Zohra S LassiZulfiqar A Bhutta
Apr 25, 2014·Journal of Nutritional Science and Vitaminology·Katsumi ShibataYoshiki Jinno
Oct 10, 2015·The Journal of Nutrition·Lynn B BaileyDaniel J Raiten
Sep 26, 2000·BJOG : an International Journal of Obstetrics and Gynaecology·J R HigginsM R Darling
Oct 5, 2011·Nutrition Reviews·Stephanie M C WilsonLynn B Bailey
May 26, 2001·Annual Review of Nutrition·J R SuhP J Stover
Mar 29, 2003·The American Journal of Clinical Nutrition·Judith M WolfeGail P A Kauwell
Jun 11, 2002·Annual Review of Nutrition·Jesse F Gregory, Eoin P Quinlivan
Jul 11, 2012·Annals of Nutrition & Metabolism·Madhavi DhobaleSadhana Joshi
Sep 9, 2000·The Journal of Biological Chemistry·J R SuhP J Stover
Apr 19, 2020·Medical Hypotheses·Justin Donhauser
Apr 14, 2020·Chemico-biological Interactions·Jaspreet Sharma, Sergey A Krupenko
Oct 24, 2001·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·H TapieroD Machover

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