Folate Receptor-Targeted Theranostic Nanoconstruct for Surface-Enhanced Raman Scattering Imaging and Photodynamic Therapy

ACS Omega
Andrew M FalesTuan Vo-Dinh

Abstract

We report the synthesis of a folate receptor (FR)-targeted theranostic nanocomposite for surface-enhanced Raman scattering (SERS) imaging and photodynamic therapy (PDT). FR-specific SERS detection and PDT are demonstrated in vitro using two FR-positive cancer cell lines and one FR-negative cancer cell lines.

References

May 2, 2003·Nature Reviews. Cancer·Dennis E J G J DolmansRakesh K Jain
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May 11, 2013·Molecular Pharmaceutics·Andrew M FalesTuan Vo-Dinh
May 2, 2014·Journal of Controlled Release : Official Journal of the Controlled Release Society·Ju Hee RyuIck Chan Kwon
May 8, 2014·The Journal of Physical Chemistry. C, Nanomaterials and Interfaces·Andrew M FalesTuan Vo-Dinh
Dec 1, 2004·Photodiagnosis and Photodynamic Therapy·Ana P CastanoMichael R Hamblin
Oct 16, 2014·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Tuan Vo-DinhGuy D Griffin
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Mar 15, 2015·Theranostics·Arash FarhadiGang Zheng
Sep 1, 2015·Nano Letters·Alessia PallaoroMartin Moskovits

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Citations

Apr 10, 2018·Current Opinion in Chemical Biology·Lucas A LaneShuming Nie
Dec 12, 2018·Journal of the American Chemical Society·Nicolas MaciaBelinda Heyne

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Methods Mentioned

BETA
surface-enhanced Raman scattering
transmission electron microscopy
environmental stresses

Software Mentioned

WiRE

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