PMID: 15244857Jul 13, 2004Paper

Folding and form: insights from lattice simulations

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
P F N FaíscaR C Ball

Abstract

Monte Carlo simulations of a Miyazawa-Jernigan lattice-polymer model indicate that, depending on the native structure's geometry, the model exhibits two broad classes of folding mechanisms for two-state folders. Folding to native structures of low contact order is driven by backbone distance and is characterized by a progressive accumulation of structure towards the native fold. By contrast, folding to high contact order targets is dominated by intermediate stage contacts not present in the native fold, yielding a more cooperative folding process.

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Citations

Dec 3, 2008·The Journal of Chemical Physics·P F N FaíscaE I Shakhnovich
Oct 16, 2007·The Journal of Chemical Physics·Rui D M TravassoPatrícia F N Faísca
Mar 9, 2005·Biophysical Chemistry·P F N Faisca, M M Telo da Gama
Dec 17, 2014·Advances in Colloid and Interface Science·Eli RuckensteinGanesan Narsimhan
May 5, 2007·The Journal of Chemical Physics·Lidia Prieto, Antonio Rey
Jul 23, 2008·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Alexander S Balankin, Orlando Susarrey Huerta
Jan 4, 2013·Physical Biology·Heinrich Krobath, Patrícia F N Faísca
Sep 16, 2009·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Patrícia F N Faísca
Nov 3, 2020·Frontiers in Molecular Biosciences·Rui J S Loureiro, Patrícia F N Faísca
Feb 18, 2020·Biophysical Journal·Daniel Trotter, Stefan Wallin

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