Follicular Unit Grafting in Chronic Nonhealing Leg Ulcers: A Clinical Study

Journal of Cutaneous and Aesthetic Surgery
Leelavathy BudamakuntlaH V Nataraj

Abstract

The restoration of the epithelium after injury takes place by migration of epithelial cells adjoining a wound or by centrifugal migration from hair follicles. To evaluate the feasibility and potential healing capacity of scalp follicular unit grafts transplanted into the wound bed of chronic leg ulcers. Patients with chronic nonhealing ulcers of more than 6 weeks duration were selected for the study. Those with infected ulcers and uncontrolled diabetes were excluded from the study. Fifteen patients were included in the study. Follicular unit grafts were harvested under local anesthesia using small-diameter (1 mm) circular punches. A density of 5 follicular grafts/cm2was implanted into the ulcer bed. The ulcer was dressed with Vaseline gauze and elastic bandage for 24 h. The wound area and volume were calculated by length × width × 0.7854 and length × width × depth × 0.7854, respectively. The treatment outcome was defined as the percentage in change of area and volume of the ulcer, 18 weeks after intervention. A total of 15 patients with 17 ulcers were treated with the above method. Of these 17 ulcers, 11 were venous ulcers, 2 were pyoderma gangrenosum associated with varicose veins, 2 were traumatic ulcers, and 2 were trophic u...Continue Reading

Citations

Jan 5, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Majid AlamFrancisco Jimenez
Jun 13, 2020·Stem Cell Research & Therapy·Tong XiaoYumin Xia
Jun 12, 2020·Advances in Wound Care·Kristo Nuutila

❮ Previous
Next ❯

Methods Mentioned

BETA
ESR

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

Related Papers

Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society
Francisco JiménezAnder Izeta
© 2022 Meta ULC. All rights reserved