Follow-up in pulmonary sarcoidosis: comparison between HRCT and pulmonary function tests.

La Radiologia medica
G GafàC Rossi

Abstract

The authors assessed the clinical usefulness of high-resolution computed tomography (HRCT) for monitoring sarcoidosis by comparing changes on HRCT with those on pulmonary function test (PFT) results over time. The baseline and follow-up (after 13 months, range 15-63 months) HRCT scans of 14 consecutive patients with sarcoidosis were reviewed by a single observer. Each follow-up HRCT examination was assessed as stable, improved (when the extent of HRCT findings was reduced compared with baseline) and worsened (when the extent of HRCT findings was increased and/or when HRCT pattern had become fibrotic compared with baseline). Any increase or decrease in forced vital capacity (FVC)≥10% from baseline was considered significant. Changes on HRCT were then compared with those on FVC. During a median follow-up of 33 (range 15-63) months, HRCT findings worsened in 8/14 (58%) cases, improved in 3/14 (21%) and remained stable in 3/14 (21%). Agreement between changes on HRCT and FVC was moderate (κ=0.49). In 9/14 (64%) cases, HRCT changes were in line with those on FVC. In 4/5 discordant cases, the worsened HRCT findings were not mirrored by FVC changes. Despite the small size of our study population, our results suggest that HRCT may prov...Continue Reading

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Citations

Oct 29, 2005·American Journal of Respiratory and Critical Care Medicine·Mostafa GhaneiJafar Aslani
Jan 9, 2014·European Radiology·Paolo SpagnoloDavid M Hansell
Feb 4, 2014·La Radiologia medica·Giorgia DalpiazLibero Barozzi
Aug 21, 2013·Annals of the American Thoracic Society·Karen C Patterson, Mary E Strek
Mar 3, 2015·Clinical Reviews in Allergy & Immunology·Mario SilvaNicola Sverzellati
Jun 16, 2017·European Respiratory Review : an Official Journal of the European Respiratory Society·Brett M ElickerTravis S Henry
Aug 11, 2020·Seminars in Respiratory and Critical Care Medicine·Rohit Gupta, Robert P Baughman
Nov 11, 2017·La Radiologia medica·Diletta CozziVittorio Miele
May 16, 2019·Expert Opinion on Pharmacotherapy·Marta LlabresJacobo Sellares

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