Follow-up of pregnancy in acromegalic women: different presentations and outcomes

Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association
A AtmacaT Erbas

Abstract

Pregnancy in acromegaly is a rather rare event since the fertility is reduced in acromegalic women. Besides, metabolic complications of acromegaly are harmful to both mother and fetus. Little is known about the outcome of pregnancy in acromegalic women. Here, we report seven cases of pregnancy out of 48 acromegalic women followed for 16 years. At diagnosis, five patients had macroadenoma, one patient had microadenoma and the size of the tumor was not documented in one patient. In one patient, acromegaly was initially diagnosed during pregnancy at 29 weeks. When she was 33 weeks, she developed pituitary apoplexy and had an emergency transsphenoidal resection of her macroadenoma during which she also had a cesarian section and delivered a healthy baby girl. In the remaining six patients, pregnancy occurred 6 to 64.5 months after the adenoma resection. Three patients received radiotherapy before getting pregnant. In three patients, pregnancy occurred during bromocriptine treatment and the drug was withdrawn. In one patient, pregnancy occurred during chronic octreotide treatment and therapeutic abortion was performed. In another patient, therapeutic abortion was performed because of uncontrolled disease. In the remaining four patie...Continue Reading

Citations

Jul 27, 2011·Pituitary·Vicky ChengAmir Hamrahian
Nov 20, 2013·European Journal of Endocrinology·Monike DiasJulio Abucham
Feb 6, 2014·Journal of Endocrinological Investigation·Rosario PivonelloGaetano Lombardi
Nov 21, 2009·Annales d'endocrinologie·L Ben Salem HachmiC Ben Slama
Nov 28, 2012·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Elena Valassi
Nov 26, 2011·Best Practice & Research. Clinical Endocrinology & Metabolism·Zuleyha Karaca, Fahrettin Kelestimur
Sep 23, 2009·Clinical Endocrinology·Pietro MaffeiNicola Sicolo
Mar 4, 2015·Endocrinology and Metabolism Clinics of North America·Paula Bruna AraujoMônica R Gadelha
Aug 12, 2016·Obstetric Medicine·Sophie Grand'MaisonAriane Godbout
Aug 12, 2016·Obstetric Medicine·Angela AssalErin Keely
Dec 2, 2015·Therapeutic Advances in Endocrinology and Metabolism·Bashir A Laway
Mar 16, 2017·European Journal of Endocrinology·Julio AbuchamMonike L Dias
Mar 27, 2018·Clinical Endocrinology·R S JalladM D Bronstein
Mar 16, 2011·Nature Reviews. Endocrinology·Marcello D BronsteinRaquel S Jallad
Jan 31, 2019·Expert Review of Endocrinology & Metabolism·Philippe ChansonPhilippe Caron
Jan 14, 2012·Endocrine Journal·Leandro KasukiMônica R Gadelha
Aug 8, 2019·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Seda Hanife OguzTomris Erbas
Jan 11, 2020·Hormone Molecular Biology and Clinical Investigation·Sebastião Freitas de MedeirosMárcia Marly Winck Yamamoto
Jun 22, 2017·Journal of Endocrinological Investigation·Z KaracaF Kelestimur
May 23, 2019·Endocrinology, Diabetes & Metabolism Case Reports·Anne Marie HannonUNKNOWN Irish Pituitary Database Group
Apr 18, 2015·Hormones : International Journal of Endocrinology and Metabolism·Alexandra ChrisoulidouJohn Wass
Oct 18, 2007·Current Opinion in Endocrinology, Diabetes, and Obesity

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