Fondaparinux is a safe alternative in case of heparin intolerance during pregnancy

Blood
Lucia MazzolaiMichel A Duchosal

Abstract

Heparin is the drug of choice for the treatment or the prevention of thromboembolic disease during pregnancy. However, treatment options are limited when heparin cannot be used because of hypersensitivity skin reactions. Despite the recent availability of new anticoagulant agents, data relating to their use during pregnancy are lacking. This report describes the successful management with fondaparinux, during 150 days, of a pregnant patient with protein S deficiency and prior deep vein thrombosis (DVT) who developed heparin and danaparoid hypersensitivity.

References

Jan 12, 2000·Gynecologic and Obstetric Investigation·G HuhleJ Harenberg
Oct 18, 2002·Clinical Pharmacokinetics·Richard A FaaijAdam F Cohen
Apr 8, 2003·Thrombosis Research·Meyer-Michel Samama, Grigoris T Gerotziafas
Sep 17, 2003·Journal of Internal Medicine·M M W Koopman, H R Büller
Dec 18, 2003·Contact Dermatitis·Ralf J LudwigWolf-Henning Boehncke
Apr 30, 2004·The New England Journal of Medicine·Carl-Erik H Dempfle
Jul 28, 2004·Contact Dermatitis·Katrin HirschWolf-Henning Boehncke
Aug 31, 2004·Journal of Thrombosis and Haemostasis : JTH·R Mehta, A Golichowski
Oct 14, 2004·Contact Dermatitis·E HohensteinA J Bircher
Jan 5, 2005·Thrombosis and Haemostasis·Edelgard Lindhoff-LastHarry N Magnani

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Citations

Jul 31, 2012·Journal of Thrombosis and Thrombolysis·Connie N HessRenato D Lopes
Aug 25, 2012·International Journal of Obstetric Anesthesia·N HimeH Bouaziz
Jun 13, 2008·Leukemia·G Garcia-ManeroS Sharma
Nov 17, 2007·Current Opinion in Obstetrics & Gynecology·Philippe Deruelle, Capucine Coulon
Jul 6, 2010·Current Opinion in Hematology·Karen M Hook, Charles S Abrams
Dec 17, 2009·Hematology·Andra H James
Apr 29, 2011·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Michał CiurzyńskiPiotr Pruszczyk
Sep 30, 2009·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Marc SchindewolfRalf J Ludwig
Mar 22, 2014·Drug Discoveries & Therapeutics·Zhang LiuFengshan Wang
Jun 19, 2010·Journal of Perinatology : Official Journal of the California Perinatal Association·A J Butwick, B Carvalho
Oct 10, 2009·Current Opinion in Endocrinology, Diabetes, and Obesity·Annemarie E Fogerty, Jean M Connors
Nov 18, 2008·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Céline MontavonDimitrios A Tsakiris
Nov 27, 2010·Expert Review of Cardiovascular Therapy·Wee Shian Chan
Dec 4, 2009·Expert Review of Cardiovascular Therapy·Jill Newstead-Angel, Paul S Gibson
Jun 21, 2013·Expert Review of Hematology·Shannon M Bates
Jun 10, 2009·Expert Review of Cardiovascular Therapy·Sunil K NadarGregory Y H Lip
Apr 1, 2009·Expert Review of Hematology·Nina Raju, Shannon M Bates
Jan 19, 2016·Journal of Thrombosis and Thrombolysis·Shannon M BatesIan Greer
Jul 21, 2012·Cardiology Clinics·Sorel Goland, Uri Elkayam
Nov 16, 2011·Critical Care Clinics·Julia A M Anderson, Jeffrey I Weitz
Oct 28, 2011·Thérapie·Céline ChauleurPatrick Mismetti
Oct 18, 2011·Seminars in Hematology·Shannon M Bates
Mar 30, 2011·Hematology/oncology Clinics of North America·Annemarie E Fogerty, Jean M Connors
Feb 1, 2011·Clinics in Chest Medicine·C Randall Lane, Terence K Trow
Nov 5, 2010·Clinics in Chest Medicine·Julia A M Anderson, Jeffrey I Weitz
Mar 6, 2010·International Journal of Obstetric Anesthesia·A J Butwick, B Carvalho
Dec 4, 2009·Leukemia Research·Alexey V DanilovKenneth B Miller
Jul 25, 2009·International Journal of Obstetric Anesthesia·A EkbataniA M Malinow
Dec 3, 2008·International Journal of Obstetric Anesthesia·Leinani Aiono-Le Tagaloa, Brendan Carvalho
Oct 11, 2008·Thrombosis Research·E Libby
May 29, 2007·Seminars in Perinatology·Andra H JamesHaywood Brown
Aug 26, 2009·American Journal of Reproductive Immunology : AJRI·Edward E Winger, Jane L Reed
Jun 6, 2008·Journal of Thrombosis and Haemostasis : JTH·J P Patel, B J Hunt
May 25, 2010·Journal of Thrombosis and Haemostasis : JTH·H M KnolK Meijer
Mar 3, 2012·The Journal of Obstetrics and Gynaecology Research·Kenji TanimuraHideto Yamada
Oct 2, 2014·British Journal of Haematology·Esra ElsaighLouise Byrd
Sep 26, 2015·Birth Defects Research. Part C, Embryo Today : Reviews·Barbara A Konkle
Oct 16, 2007·The American Journal of Medicine·Andra H James
Apr 29, 2015·Thrombosis Research·S De CarolisV De Stefano
Dec 3, 2011·Thrombosis Research·Michael NaglerWalter A Wuillemin
Jun 1, 2013·Obstetric Medicine·Ai-Wei Tang, Ian Greer
Oct 7, 2015·Circulation·Christina D YarringtonKatherine E Economy

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