Fondaparinux: the present and the future

Pathologie-biologie
C Garcia HejlV Foissaud

Abstract

The development of new antithrombotic molecules which induced an inhibition of activated factor X (fondaparinux, Arixtra) shows effectiveness and safety in prevention of thromboembolic disease in surgery, but also in the treatment of the pulmonary embolism and major venous thromboses and acute myocardial infarction. Recent clinical trials show that new anti-Xa inhibitors also have interesting properties in antithrombotic therapy. Fondaparinux could offer new therapeutic possibilities that could simplify the management of patients under anticoagulant treatment.

References

Mar 1, 1997·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·J AmiralD Meyer
Oct 31, 2001·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·G T GerotziafasM M Samama
Jan 17, 2002·The New England Journal of Medicine·B I ErikssonUNKNOWN Steering Committee of the Pentasaccharide in Hip-Fracture Surgery Study
Jan 17, 2002·The New England Journal of Medicine·K A BauerUNKNOWN Steering Committee of the Pentasaccharide in Major Knee Surgery Study
Jun 7, 2002·Lancet·Henri Bounameaux, Thomas Perneger
Jun 7, 2002·Lancet·Michael Rud LassenUNKNOWN European Pentasaccharide Elective Surgery Study (EPHESUS) Steering Committee
Apr 8, 2003·Thrombosis Research·Meyer-Michel Samama, Grigoris T Gerotziafas
Jun 11, 2003·Archives of Internal Medicine·Bengt I ErikssonUNKNOWN PENTasaccharide in HIp-FRActure Surgery Plus Investigators
Oct 31, 2003·The New England Journal of Medicine·H R BüllerUNKNOWN Matisse Investigators
Nov 15, 2003·Lancet·Alexander G G TurpieMichael R Lassen
Jan 23, 2004·La Revue de médecine interne·Y Gruel
Jun 3, 2004·Annals of Internal Medicine·Harry R BüllerUNKNOWN Matisse Investigators
Jun 12, 2004·Blood·Jack HirshJeffrey I Weitz
Jun 15, 2004·Journal of the American College of Cardiology·Maarten L SimoonsUNKNOWN PENTUA Investigators
Sep 25, 2004·Archives of Pathology & Laboratory Medicine·Robert C GosselinJohn T Owings
Aug 9, 2005·Hematology·K H M Kuo, M J Kovacs
Feb 14, 2006·Journal of Thrombosis and Thrombolysis·Sarah A Spinler
Jun 22, 2006·The Annals of Pharmacotherapy·Leigh E Efird, Denise R Kockler
Jun 5, 2007·Pharmacotherapy·Stella PapadopoulosDaniel A Lewis
Jun 22, 2007·The New England Journal of Medicine·Theodore E WarkentinRichard H Aster

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.