Fontan-Associated Liver Disease: A Review.

Annals of Hepatology
Luis TéllezAgustín Albillos

Abstract

Fontan-associated liver disease is a hepatic disorder arising from hemodynamic changes and systemic venous congestion following Fontan surgery. The histological changes produced in the liver are similar but not equivalent to those seen in other forms of cardiac liver disease. While the natural history of this form of liver disease is not well established, over time many Fontan patients develop portal hypertension-related complications such as ascites, variceal hemorrhage or encephalopathy. Fontan survivors also show an increased risk of hepatocellular carcinoma. Early diagnosis of advanced liver disease is mandatory for the prevention and treatment of complications such as hepatocellular carcinoma, esophageal varices and malnutrition. This review updates current knowledge of the pathophysiology and management of Fontan-associated liver disease including new diagnostic methods and treatments.

Citations

Jan 9, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Enrique Rodríguez de SantiagoAgustín Albillos
Mar 29, 2020·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Takaomi SagawaKatsutoshi Tokushige
May 15, 2020·Cardiology in the Young·Renate KaulitzMichael Hofbeck
Aug 11, 2020·Current Opinion in Organ Transplantation·Ryan E HoferJames Y Findlay
Aug 3, 2020·Pediatric Cardiology·Saviga SethasathienYupada Pongprot
Oct 11, 2020·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Enrique Rodriguez De SantiagoAgustín Albillos
Jan 17, 2021·Radiología·M J Parada BlázquezB Vargas Serrano
Dec 12, 2020·Scientific Reports·Tomomi Kogiso, Katsutoshi Tokushige
Jul 27, 2021·Radiology Case Reports·Fulvio GasparriniAntonio Orlacchio
Aug 17, 2021·Seminars in Liver Disease·Luis TéllezAgustín Albillos
Jul 26, 2019·Case Reports in Gastroenterology·Brian Patrick RutledgeMurray Ehrinpreis

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