Food allergy in the Netherlands: differences in clinical severity, causative foods, sensitization and DBPCFC between community and outpatients

Clinical and Translational Allergy
Thuy-My LeA C Knulst

Abstract

It is unknown whether food allergy (FA) in an unselected population is comparable to those from an outpatient clinic population. To discover if FA in a random sample from the Dutch community is comparable to that of outpatients. This study was part of the Europrevall-project. A random sample of 6600 adults received a questionnaire. Those with symptoms to one of 24 defined priority foods were tested for sIgE. Participants with a positive case history and elevated sIgE were evaluated by double-blind placebo-controlled food challenge (DBPCFC). Outpatients with a suspicion of FA were evaluated by questionnaire, sIgE and DBPCFC. In the community, severe symptoms were reported less often than in outpatients (39.3% vs. 54.3%). Participants in the community were less commonly sensitized to any of the foods. When selecting only those with a probable FA (i.e. symptoms of priority food and elevation of sIgE to the respective food), no major differences were observed with respect to severity, causative foods, sensitization and DBPCFC between the groups. In the Netherlands, there are large differences in self-reported FA between community and outpatients. However, Dutch community and outpatients with a probable FA do not differ with respect...Continue Reading

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Citations

May 14, 2020·PloS One·Cornelia Doriene Westerlaken-van GinkelAnthony E J Dubois
Mar 28, 2018·Analytical and Bioanalytical Chemistry·Georgina M S RossMichel W F Nielen
Apr 4, 2021·Nutrients·Daniela Briceno Noriega, Huub F J Savelkoul
Jul 22, 2021·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Hannah M KansenThuy-My Le

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Software Mentioned

EuroPrevall
SPSS

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