Food Antioxidants: Chemical Insights at the Molecular Level

Annual Review of Food Science and Technology
Annia GalanoNino Russo

Abstract

In this review, we briefly summarize the reliability of the density functional theory (DFT)-based methods to accurately predict the main antioxidant properties and the reaction mechanisms involved in the free radical-scavenging reactions of chemical compounds present in food. The analyzed properties are the bond dissociation energies, in particular those involving OH bonds, electron transfer enthalpies, adiabatic ionization potentials, and proton affinities. The reaction mechanisms are hydrogen-atom transfer, proton-coupled electron transfer, radical adduct formation, single electron transfer, sequential electron proton transfer, proton-loss electron transfer, and proton-loss hydrogen-atom transfer. Furthermore, the chelating ability of these compounds and its role in decreasing or inhibiting the oxidative stress induced by Fe(III) and Cu(II) are considered. Comparisons between theoretical and experimental data confirm that modern theoretical tools are not only able to explain controversial experimental facts but also to predict chemical behavior.

References

Jan 1, 1986·Annual Review of Physiology·W A Pryor
Nov 15, 1985·Archives of Biochemistry and Biophysics·W A PrützE J Land
May 1, 1995·Biochemical Society Transactions·S A EverettR L Willson
Jan 1, 1996·Chemical Research in Toxicology·D C Liebler, T D McClure
Sep 19, 1998·Free Radical Biology & Medicine·G L Squadrito, W A Pryor
Feb 22, 2001·Free Radical Biology & Medicine·R RadiA Cayota
Jun 9, 2004·International Journal of Radiation Oncology, Biology, Physics· VijayalaxmiCharles R Thomas
Feb 11, 2005·Organic & Biomolecular Chemistry·Ikuo NakanishiNobuo Ikota
Aug 17, 2006·Journal of Agricultural and Food Chemistry·Monica LeopoldiniMarirosa Toscano
Apr 25, 2007·Critical Reviews in Food Science and Nutrition·Wilailuk ChaiyasitEric A Decker
Aug 22, 2007·Journal of Agricultural and Food Chemistry·Monica LeopoldiniMarirosa Toscano
Dec 7, 2007·Chemical Research in Toxicology·Lawrence M SayreMark A Smith
Feb 20, 2009·Angewandte Chemie·Chryssostomos ChatgilialogluQuinto G Mulazzani
Mar 12, 2009·The Journal of Organic Chemistry·Malgorzata MusialikGrzegorz Litwinienko
Aug 12, 2009·Chemico-biological Interactions·Surajdevprakash B DhimanDevidas B Naik
Dec 22, 2009·Physical Chemistry Chemical Physics : PCCP·Annia GalanoAna Martínez
Jun 2, 2010·Chemical Society Reviews·Marco Lucarini, Gian Franco Pedulli
Jul 3, 2010·Physical Chemistry Chemical Physics : PCCP·Sandro G ChiodoMarirosa Toscano
Jul 9, 2010·The Journal of Physical Chemistry. B·Laura EstévezRicardo A Mosquera
Aug 5, 2010·Journal of Agricultural and Food Chemistry·Monica LeopoldiniMarirosa Toscano
Mar 1, 2011·The Journal of Physical Chemistry. a·Andrew Sirjoosingh, Sharon Hammes-Schiffer
Mar 17, 2011·Physical Chemistry Chemical Physics : PCCP·Annia Galano
Mar 29, 2011·The Journal of Physical Chemistry. B·Jorge Rafael León-Carmona, Annia Galano
May 14, 2011·Physical Chemistry Chemical Physics : PCCP·Annia GalanoJ Raúl Alvarez-Idaboy
Sep 23, 2011·The Journal of Physical Chemistry. B·Ana MartínezRubicelia Vargas
Oct 5, 2011·The Journal of Physical Chemistry. B·Annia GalanoMisaela Francisco-Márquez
Oct 27, 2011·Antiviral Research·Rekha G PanchalSina Bavari
Dec 23, 2011·The Journal of Physical Chemistry. B·Annia Galano, Ana Martínez
Dec 23, 2011·The Journal of Physical Chemistry. B·Adriana Pérez-González, Annia Galano
Apr 19, 2012·Physical Chemistry Chemical Physics : PCCP·Jorge Rafael León-CarmonaAnnia Galano
Jul 14, 2012·The Journal of Organic Chemistry·Jason J HanthornDerek A Pratt
Sep 8, 2012·Food Chemistry·Zoran MarkovićDragan Amić

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Citations

Jul 19, 2016·The Journal of Physical Chemistry. a·César EspinozaManuel E Medina
Nov 2, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Annia GalanoRussel J Reiter
Feb 27, 2018·Organic & Biomolecular Chemistry·S JeremićZ Marković
Jun 12, 2018·Journal of Pineal Research·Annia Galano, Russel J Reiter
Jul 13, 2018·Journal of Toxicology and Environmental Health. Part a·Douglas Costa GontijoJoão Paulo Viana Leite
Oct 5, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ana BettencourtFilipe Areias
Nov 13, 2018·Journal of Pineal Research·Adriana Pérez-GonzálezAnnia Galano
Oct 17, 2019·Journal of Clinical Medicine·Raluca Ioana TeleanuDaniel Mihai Teleanu
Mar 27, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ana Karković MarkovićStanko Uršić
Mar 29, 2020·Free Radical Research·Houssem Boulebd
Aug 20, 2019·Journal of Biomolecular Structure & Dynamics·Ol'ha O Brovarets', Dmytro M Hovorun
Jul 19, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jeysson Sánchez-SuárezLuis Díaz
Aug 15, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yan-Zhen ZhengRui Guo
Apr 10, 2019·Antioxidants·Taseer Ahmad, Yuichiro J Suzuki
May 28, 2019·Journal of Molecular Modeling·K AnbazhakanM Dhandapani
Jun 27, 2017·Biomimetics·Riccardo AmoratiLuca Valgimigli
Jun 27, 2019·Journal of Molecular Modeling·María F Manrique-de-la-CubaBadhin Gómez
Apr 29, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zhi-Yin YangLeif H Skibsted
Jul 10, 2020·Antioxidants·Jelena Tošović, Urban Bren
May 26, 2017·Physical Chemistry Chemical Physics : PCCP·Cristina Ortega-MooRubicelia Vargas
Dec 20, 2018·Royal Society Open Science·Vladimir P PetrovićZorica D Petrović
Apr 30, 2020·Antioxidants·Isabella RomeoTiziana Marino
Jul 3, 2020·International Journal of Molecular Sciences·Francesca AnnunziataAndrea Pinto
Apr 22, 2017·Scientific Reports·Ruslan Álvarez-DidukArben Merkoçi
Sep 28, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Seyedmohammad AhmadiMarirosa Toscano
Jan 19, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rui ChangQiu-Jin Zhu
Mar 12, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lijuan YangShifa Wang
Feb 9, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jie LiuDongfeng Chen
Aug 31, 2019·BioMed Research International·Thamizhiniyan VenkatesanYoung-Kyoon Kim
Jan 7, 2021·Organic & Biomolecular Chemistry·Sofia ShkunnikovaDavor Šakić
Dec 19, 2020·Comprehensive Reviews in Food Science and Food Safety·Mădălina Iuga, Silvia Mironeasa

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Methods Mentioned

BETA
PCET
SPLHAT

Software Mentioned

SPLET

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