PMID: 15374480Sep 1, 1990Paper

Food restriction in female Wistar rats. I. Survival characteristics, membrane microviscosity and proliferative response in lymphocytes

Archives of Gerontology and Geriatrics
C PieriL Piantanelli

Abstract

The effect of food restriction on the survival characteristics, membrane microviscosity and proliferative response in lymphocytes of female Wistar undernourished rats has been evaluated. Diet restriction was applied starting from the age of 3.5 months by feeding the animals on an every-other-day schedule (EOD). Diet restricted animals showed an increase of both mean, median and maximal life span as compared to the rats fed ad libitum (AL). Analyzing the survival curves by a parametric model, it emerged that undernutrition increased the individual resistance to environmental insults. In particular, it could be speculated that the positive influence was more pronounced in individuals with the lowest physiological capacities. The membrane microviscosity of lymphocytes was lower in EOD animals as compared to the AL ones even if one assumes a decrease in body temperature of 1-2 degrees C in EOD groups. The improvement of membrane microviscosity due to diet restriction may in part explain the improvement of proliferative response of lymphocytes from EOD groups.

References

Dec 15, 1978·Biochimica Et Biophysica Acta·M Shinitzky, Y Barenholz
Aug 15, 1977·Biochimica Et Biophysica Acta·M L Maccecchini, M M Burger
Apr 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·G FernandesR A Good
Mar 11, 1976·Journal of Gerontology·S LetoC H Barrows
Jul 1, 1986·Archives of Gerontology and Geriatrics·L Piantanelli
Jan 1, 1984·Molecular and Cellular Biochemistry·R Salesse, J Garnier
Jan 1, 1982·Gerontology·C L GoodrickN L Cider
Feb 1, 1980·Mechanisms of Ageing and Development·B RivnayA Globerson
Jan 1, 1980·Experimental Gerontology·K E CheneyR L Walford

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Citations

Dec 1, 1991·Aging : Clinical and Experimental Research·C PieriR Recchioni
Mar 1, 1991·Archives of Gerontology and Geriatrics·C PieriF Marcheselli
Sep 1, 1991·Archives of Gerontology and Geriatrics·C PieriR Recchioni
Jan 1, 1992·Archives of Gerontology and Geriatrics·C PieriG Lupidi
May 1, 1992·Archives of Gerontology and Geriatrics·J H DowsonC Bertoni-Freddari
Nov 1, 1992·Comparative Biochemistry and Physiology. Comparative Physiology·C PieriF Marcheselli
Jun 1, 2000·Experimental Gerontology·W T CefaluJ Parks
Jan 1, 1991·Annals of the New York Academy of Sciences·C Pieri
Dec 26, 1992·Annals of the New York Academy of Sciences·C PieriS Damjanovich
Mar 12, 2015·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Takaaki Yamada
Dec 26, 1992·Annals of the New York Academy of Sciences·L PiantanelliA Basso
Mar 1, 1993·American Journal of Audiology·R S Tyler
Aug 1, 1992·Journal of Speech and Hearing Research·H Fryauf-BertschyB J Gantz
Apr 1, 1992·Journal of Speech and Hearing Research·P W DawsonF W Rickards
Nov 1, 1993·American Journal of Audiology·H Fryauf-Bertschy
Mar 1, 1993·American Journal of Audiology·H Fryauf-BertschyA L Weiss
Apr 7, 2018·Journal of Speech, Language, and Hearing Research : JSLHR·Arne Kirkhorn RødvikJuha Tapio Silvola
Jul 1, 2002·Language, Speech, and Hearing Services in Schools·David J ErtmerMichael L Pachuilo

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