PMID: 15374481Sep 1, 1990Paper

Food restriction in female Wistar rats. II. Beta-adrenoceptor density in the cerebellum and in the splenic lymphocytes

Archives of Gerontology and Geriatrics
C PieriR Recchioni

Abstract

The effect of diet restriction, applied on an every-other-day schedule from 3.5 months of age on, has been investigated on the beta-adrenoceptor density in the cerebellum and in the splenic lymphocytes of old female Wistar rats. Comparing animals 6 months and 24 months old fed ad libitum, a 75% age-dependent reduction in specific binding of the agonist dihydroalprenolol was observed in cerebellar membrane preparations, while the beta-adrenoceptor density of lymphocytes remained unaltered. Diet restriction induced a partial recovery of the age-related decrease of this parameter in the cerebellum without affecting the receptor density of lymphocytes. Present results suggest that undernutrition delays the appearance of those alterations related to aging.

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Citations

Jan 1, 1991·Annals of the New York Academy of Sciences·C Pieri
Oct 19, 2007·Journal of Neurosurgery·Bertrand BaussardChristian Sainte-Rose
Jun 3, 2009·Journal of Neurosurgery. Pediatrics·Mostafa El KhashabDaniel C Bowers
Aug 1, 1991·Circulation·A MallianiS Cerutti
Jan 18, 2011·Journal of Neurosurgery·Jamie J Van GompelCaterina Giannini

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